" /> ERBB2 wt Allele - CISMeF





Preferred Label : ERBB2 wt Allele;

NCIt synonyms : V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) Gene; HER2; NGL; c-ERBB-2; NEU Gene; Human EGF Receptor 2 Gene; TKR1; HER2/neu; ERBB2; Erb-b2 Receptor Tyrosine Kinase 2 wt Allele;

NCIt definition : Human ERBB2 wild-type allele is located in the vicinity of 17q21.1 and is approximately 29 kb in length. This allele, which encodes receptor tyrosine-protein kinase erbB-2 protein, plays a role in EGF receptor signal transduction pathways and cellular growth. Amplification or overexpression of this gene is involved in the progression of several forms of cancer, including breast and ovarian tumors.;

GenBank Accession Number : NM_004448;

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12/05/2024


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