" /> Calcium-Mediated Signaling Pathway - CISMeF





Preferred Label : Calcium-Mediated Signaling Pathway;

NCIt related terms : Calcium signaling pathway;

Alternative definition : KEGG: Ca2 that enters the cell from the outside is a principal source of signal Ca2 . Entry of Ca2 is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this external source of signal Ca2 by activating various entry channels with widely different properties. The voltage-operated channels (VOCs) are found in excitable cells and generate the rapid Ca2 fluxes that control fast cellular processes. There are many other Ca2 -entry channels, such as the receptor-operated channels (ROCs), for example the NMDA (N-methyl-D-aspartate) receptors (NMDARs) that respond to glutamate. There also are second-messenger-operated channels (SMOCs) and store-operated channels (SOCs).;

KEGG ID : hsa04020;

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30/07/2025


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