TFF1 wt Allele

Preferred Label : TFF1 wt Allele;

NCIt synonyms : pS2; Trefoil Factor 1 (Breast Cancer, Estrogen-Inducible Sequence Expressed In) Gene; pNR-2; BCEI; HPS2; D21S21; Trefoil Factor 1 wt Allele; Breast Cancer, Estrogen-Inducible Sequence Expressed In Gene; HP1.A; Breast Cancer Estrogen-Inducible Sequence Gene;

NCIt definition : Human TFF1 wild-type allele is located in the vicinity of 21q23.1 and is approximately 4 kb in length. This allele, which encodes trefoil factor 1 protein, is involved in gastrointestinal mucosa stabilization. Wild type allele dysfunction, including altered expression, deletion, and/or mutation, is observed frequently in human gastric carcinomas.;

GenBank Accession Number : NM_003225;

Details

Origin ID

C52116;

UMLS CUI

C1705334;

OMIM relation
- Trefoil factor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Gastric Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 21q22.3 [NCIt concept]
gene_is_biomarker_type
- Prognostic Factor [NCIt concept]
- Tumor Marker [NCIt concept]
gene_is_element_in_pathway
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- LKB1 Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Progression [NCIt concept]
- Cell Maintenance [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Regeneration [NCIt concept]

Keyword's position in hierarchy(ies) :

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