Catechol O-Methyltransferase

Preferred Label : Catechol O-Methyltransferase;

NCIt synonyms : EC 2.1.1.6; COMT; Catechol-O-Methyltransferase;

NCIt definition : Catechol O-methyltransferase (271 aa, 30 kDa) is encoded by the human COMT gene. This protein is involved in the metabolism of neurotransmitters.;

Détails

Origin ID

C16387;

UMLS CUI

C3850446;

Currated CISMeF NLP mapping
- Catechol-o-methyltransferase [OMIM Phenotype]
- catechol-O-methyltransferase [ORDO Gene]
False automatic mappings
- catechol O-Methyltransferase [MeSH Descriptor]
- catechol O-Methyltransferase [MeSH concept]
OMIM relation
- Catechol-o-methyltransferase [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- COMT protein, human [MeSH Supplementary Concept]
- COMT protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- COMT Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Liver [NCIt concept]
- Placenta [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Metal Binding Site [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
- Tyrosine Metabolism Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Metabolism [NCIt concept]
- Methylation [NCIt concept]
is_target
- Tolcapone [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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