Catechol-o-methyltransferase

Preferred Label : Catechol-o-methyltransferase;

Symbol : COMT;

CISMeF acronym : COMT;

Type : Gene and phenotype, combined;

Included titles and symbols : Catechol-o-methyltransferase activity, low, in red cells;

Description : Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines (summary by Gogos et al., 1998). COMT catalyzes the transfer of a methyl group from S-adenosyl-methionine (SAM) to a hydroxyl group on a catechol nucleus (e.g., dopamine, norepinephrine, or catechol estrogen) (summary by Chen et al., 2004).;

Inheritance : Autosomal recessive (22q11.2);

Prefixed ID : 116790;

Détails

Origin ID

116790;

UMLS CUI

C1135159;

Automatic exact mappings (from CISMeF team)
- COMT Gene [NCIt concept]
- COMT gene [LOINC component]
- County [NCIt concept]
- catechol-O-methyltransferase [HGNC gene]
- geography [MeSH Descriptor]
Currated CISMeF NLP mapping
- Catechol O-Methyltransferase [NCIt concept]
- catechol O-Methyltransferase [MeSH Descriptor]
- catechol O-Methyltransferase [MeSH concept]
- catechol-O-methyltransferase [ORDO Gene]
False automatic mappings
- Catechol methyltransferase (substance) [SNOMED CT concept]
NCIt concept(s)
- COMT Gene [NCIt concept]
- COMT wt Allele [NCIt concept]
- Catechol O-Methyltransferase [NCIt concept]
ORDO concept(s)
- catechol-O-methyltransferase [ORDO Gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- COMT Gene [NCIt concept]
- COMT gene [LOINC component]
- catechol-O-methyltransferase [HGNC gene]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients