Cadherin-1 - CISMeF

Preferred Label : Cadherin-1;

NCIt synonyms : Uvomorulin; Liver Cell Adhesion Molecule; Epithelial-Cadherin; Epithelial Calcium-Dependent Adhesion Protein; CDH1; CAM 120/80; E-Cadherin; Cadherin 1; CD324; Epithelial Cadherin; CD324 Antigen;

NCIt definition : Cadherin-1 (882 aa, 97 kDa) is encoded by the human CHD1 gene. This protein plays a role in the regulation of cell-cell adhesion, proliferation, and motility of epithelial cells; Cadherin-1 (882 aa, 97 kDa) is encoded by the human CHD1 gene. This protein plays a role in the regulation of cell-cell adhesion, proliferation, and motility of epithelial cells;

Details

Origin ID

C17245;

UMLS CUI

C1739912;

Currated CISMeF NLP mapping
- E-Cadherins [MeSH concept]
- E-cadherin [FMA entity]
- E-cadherin [LOINC component]
OMIM relation
- Cadherin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CDH1 protein, human [MeSH concept]
- CDH1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CDH1 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epithelium [NCIt concept]
gene_product_has_abnormality
- Loss of CDH1 Protein Expression [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Calcium Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cadherin Domain [NCIt concept]
- Cytoplasmic Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
- Tumor Marker [NCIt concept]
gene_product_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Adherens Junction Formation Pathway [NCIt concept]
- Adherens Junction Stabilization Pathway [NCIt concept]
- Alpha6/Beta1 and Alpha6/Beta4 Integrin Signaling Pathway [NCIt concept]
- Arf6 Trafficking Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- E-Cadherin Signaling Pathway in Keratinocytes [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Hippo Signaling Pathway [NCIt concept]
- MTA3 Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Nectin Adhesion Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Sumoylation in Modulation of CtBP-Dependent Gene Response Pathway [NCIt concept]
- TGF Beta Signaling Pathway BioCarta [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Colorectal Carcinoma [NCIt concept]
- Malignant Ovarian Neoplasm [NCIt concept]
- Thyroid Gland Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Cell Adhesion Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Metastasis Suppression [NCIt concept]
- Suppression of Cancer Cell Invasion [NCIt concept]

Keyword's position in hierarchy(ies) :

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