E3 Ubiquitin/ISG15 Ligase TRIM25

Preferred Label : E3 Ubiquitin/ISG15 Ligase TRIM25;

NCIt synonyms : EFP; TRIM25; Z147; Tripartite Motif Protein TRIM25; Estrogen-Responsive Finger Protein; ZNF147; Zinc Finger Protein-147; Tripartite Motif-Containing 25; EC 6.3.2.19, Formerly; RING Finger Protein 147; EC 6.3.2.n3, Formerly; Ubiquitin/ISG15-Conjugating Enzyme TRIM25; Zinc Finger Protein 147; Tripartite Motif-Containing Protein 25;

NCIt definition : E3 ubiquitin/ISG15 ligase TRIM25 (630 aa, 71 kDa) is encoded by the human TRIM25 gene. This protein is involved in both innate immunity and protein ubiquitination.;

Details

Origin ID

C21251;

UMLS CUI

C1384551;

Automatic exact mappings (from CISMeF team)
- Tripartite motif-containing protein 25 [OMIM gene]
- factor EF-P [MeSH Supplementary Concept]
OMIM relation
- Tripartite motif-containing protein 25 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TRIM25 protein, human [MeSH Supplementary Concept]
- TRIM25 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- TRIM25 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- TRIM Motif [NCIt concept]
gene_product_is_element_in_pathway
- EFP Cell Cycle Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of G2 to M Transition [NCIt concept]
- Proteolysis [NCIt concept]
- Signal Transduction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]
- Uterine Swelling [NCIt concept]

Keyword's position in hierarchy(ies) :

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