ADAM11 wt Allele

Preferred Label : ADAM11 wt Allele;

NCIt synonyms : A Disintegrin and Metalloproteinase Domain 11 wt Allele; MDC;

NCIt definition : Human ADAM11 wild-type allele is located in the vicinity of 17q21.3 and is approximately 21 kb in length. This allele, which encodes ADAM11 protein, plays a role in integrin binding. Expression of the ADAM 11 gene is disrupted in cancers such as breast and ovarian cancer due to gene rearrangements.;

GenBank Accession Number : NM_002390;

Details

Origin ID

C49543;

UMLS CUI

C1705375;

OMIM relation
- A disintegrin and metalloproteinase domain 11 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Malignant Ovarian Neoplasm [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 17: 40192094-40213504 [NCIt concept]
gene_in_chromosomal_location
- 17q21.3 [NCIt concept]
gene_plays_role_in_process
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Fertilization [NCIt concept]
- Hydrolysis [NCIt concept]
- Integrin Binding [NCIt concept]
- Myogenesis [NCIt concept]
- Neural Development [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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