Preferred Label : MIR21 wt Allele;
NCIt synonyms : MicroRNA 21 wt Allele; hsa-mir-21; MIRN21;
NCIt definition : The human MIR21 wild-type allele is located in the vicinity of 17q23.1 and is 71 bases
in length. This allele, which encodes MIR21 pre-miRNA, plays a role in the regulation
of gene expression. Alteration in the expression of this gene is associated with the
development of cancers of the liver, breast, esophagus, stomach, pancreas and prostate,
as well as glioblastoma, glioma and squamous cell carcinomas of the head and neck
and mouth.;
NCIt note : MIR21 is overexpressed in breast cancer, malignant human brain tumors, glioblastomas,
CLL and in cervical cancer.;
GenBank Accession Number : NT_0107837;
miRBase ID : MI0000077;
Origin ID : C81899;
UMLS CUI : C2825806;
Automatic exact mappings (from CISMeF team)
- OMIM relation
- Semantic type(s)
- gene_associated_with_disease
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_plays_role_in_process
