" /> TP53 wt Allele - CISMeF





Preferred Label : TP53 wt Allele;

NCIt synonyms : P53; TRP53; LFS1; Tumor Protein P53 (Li-Fraumeni Syndrome) wt Allele; FLJ92943; TP53; Tumor Protein p53 Gene; p53 wild type; BCC7;

NCIt related terms : p53 gene;

NCIt definition : Human TP53 wild-type allele is located in the vicinity of 17p13.1 and is approximately 19 kb in length. This allele, which encodes cellular tumor antigen p53 protein, plays a role in cell cycle regulation during the G0/G1transition. Alterations of the TP53 gene occur as both somatic and germline mutations in human malignancies in select cancer-prone families with Li-Fraumeni syndrome.;

Alternative definition : NCI-GLOSS: A tumor suppressor gene that normally inhibits the growth of tumors. This gene is altered in many types of cancer.;

GenBank Accession Number : NM_000546; AF307851;

Codes from synonyms : CDR0000045813;

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29/04/2024


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