Ampulla of Vater Adenocarcinoma

Preferred Label : Ampulla of Vater Adenocarcinoma;

NCIt synonyms : Ampullary Adenocarcinoma; Adenocarcinoma of Ampulla of Vater; Invasive Adenocarcinoma of the Ampullary Region;

NCIt definition : An invasive carcinoma with glandular differentiation arising from the ampulla of Vater. Signs and symptoms include jaundice, abdominal pain, anorexia, nausea, vomiting, and weight loss.;

Neoplastic status : Malignant;

Détails

Origin ID

C6650;

UMLS CUI

C1332243;

Automatic exact mappings (from CISMeF team)
- Adenocarcinoma of ampulla of Vater [ICD-11 Subcategory]
- Adenocarcinoma of ampulla of Vater [MedDRA LLT]
- ampulla of Vater adenocarcinoma [DO Concept]
DO Cross reference
- ampulla of Vater adenocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Abdominal Pain [NCIt concept]
- Anorexia [NCIt concept]
- Jaundice [NCIt concept]
- Lower Gastrointestinal Hemorrhage [NCIt concept]
- Malaise [NCIt concept]
- Nausea [NCIt concept]
- Pruritus [NCIt concept]
- Vomiting [NCIt concept]
- Weight Loss [NCIt concept]
Has associated anatomic sites
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Intestine [NCIt concept]
- Small Intestine [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Adenocarcinoma of ampulla of Vater [MedDRA LLT]
- ampulla of Vater adenocarcinoma [DO Concept]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Glandular Cell [NCIt concept]
- Small Intestinal Glandular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelium [NCIt concept]
- Small Intestinal Mucosa [NCIt concept]
disease_has_primary_anatomic_site
- Ampulla of Vater [NCIt concept]
- Digestive System [NCIt concept]
- Small Intestine [NCIt concept]
disease_mapped_to_gene
- KRAS Gene [NCIt concept]
- SMAD4 Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_associated_disease
- Crohn Disease [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CTNNB1 Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- Loss of CDH1 Protein Expression [NCIt concept]
- Microsatellite Instability [NCIt concept]
- SMAD4 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
pathogenesis_of_disease_involves_gene
- KRAS Gene [NCIt concept]
- KRAS wt Allele [NCIt concept]
- SMAD4 Gene [NCIt concept]
- SMAD4 wt Allele [NCIt concept]
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]

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