NCIt synonyms : DPC4; MAD Homolog 4 Gene; SMAD4/DPC4 Gene; SMAD, Mothers Against DPP Homolog 4 (Drosophila) Gene; MADH4; Mothers Against Decapentaplegic, Drosophila, Homolog, 4 Gene; MADH4 Gene; SMAD Family Member 4 wt Allele; JIP; Deleted in Pancreatic Carcinoma Locus 4 Gene; MADH4 wt Allele; MADD, Mothers Against Decapentaplegic Homolog 4 (Drosophila) Gene; Mothers Against Decapentaplegic Homolog 4 Gene; Deleted in Pancreatic Carcinoma 4 Gene; MYHRS; Deletion Target in Pancreatic Carcinoma 4 Gene;
NCIt definition : Human SMAD4 wild-type allele is located in the vicinity of 18q21.1 and is approximately
50 kb in length. This allele, which encodes mothers against decapentaplegic homolog
4 protein, plays a role in the modulation of signal transduction that is mediated
by cytokines in the transforming growth factor beta superfamily.;