Anaplastic Astrocytoma

Preferred Label : Anaplastic Astrocytoma;

NCIt synonyms : Grade III Astrocytoma; Grade III Astrocytic Neoplasm; Malignant Astrocytoma; Grade III Astrocytic Tumor; Grade 3 Astrocytic Tumor; Grade 3 Astrocytoma; High-Grade Astrocytoma; High Grade Astrocytoma; Grade 3 Astrocytic Neoplasm;

NCIt related terms : Astrocytoma, anaplastic; High-grade astrocytoma, NOS;

NCIt definition : A diffusely infiltrating, WHO grade 3 astrocytoma with focal or dispersed anaplasia, and a marked proliferative potential. It may arise from a low-grade astrocytoma, but it can also be diagnosed at first biopsy, without indication of a less malignant precursor lesion. It has an intrinsic tendency for malignant progression to glioblastoma. (WHO);

Neoplastic status : Malignant;

ICD-O code : 9401/3;

Codes from synonyms : 10008093; 10002224;

Details

Origin ID

C9477;

UMLS CUI

C0334579;

Automatic exact mappings (from CISMeF team)
- Astrocytoma grade 3 [ACR pathology]
- Astrocytoma grade 3 [ACR pathology]
- High-grade astrocytoma [ORDO Disease]
- Malignant astrocytoma [PASCAL descriptor]
- astrocytoma WHO grade III [Radlex concept]
Currated CISMeF NLP mapping
- Anaplastic astrocytoma [MedDRA Preferred Term]
- Anaplastic astrocytoma [ORDO Disease]
- Astrocytoma malignant [MedDRA Preferred Term]
- Astrocytoma malignant NOS [MedDRA LLT]
- Astrocytoma, anaplastic [ICD-O code]
- Astrocytoma, anaplastic [ICD-11 Extension code]
- Astrocytoma, anaplastic (morphologic abnormality) [SNOMED CT concept]
- Astrocytoma, anaplastic type [ICD-9 code]
- anaplastic astrocytoma [DO Concept]
- anaplastic astrocytoma [MeSH concept]
- astrocytoma [MeSH Descriptor]
- astrocytoma grade III [Disease (Nov.)]
- astrocytoma, anaplastic [SNOMED Notion]
- malignant astrocytoma [DO Concept]
DO Cross reference
- anaplastic astrocytoma [DO Concept]
Disease may have findings
- Headache [NCIt concept]
- Motor Manifestations [NCIt concept]
- Seizure [NCIt concept]
- Sensory Manifestations [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
See also inter- (CISMeF)
- Malignant astrocytoma [PASCAL descriptor]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Anaplastic astrocytoma [ORDO Disease]
- Anaplastic astrocytoma [MedDRA LLT]
- Anaplastic astrocytoma [MedDRA Preferred Term]
- Astrocytoma malignant [MedDRA Preferred Term]
- Astrocytoma malignant NOS [MedDRA LLT]
- Astrocytoma, anaplastic [ICD-O code]
- Astrocytoma, anaplastic (morphologic abnormality) [SNOMED CT concept]
- Astrocytoma, anaplastic type [ICD-9 code]
- anaplastic astrocytoma [DO Concept]
- anaplastic astrocytoma [MeSH concept]
- astrocytoma grade III [Disease (Nov.)]
- astrocytoma, anaplastic [SNOMED Notion]
Validated automatic mappings to NTBT
- Astrocytoma [PASCAL descriptor]
- astrocytoma [Disease (Nov.)]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CRF1 Registration Table [NCIt concept]
- CRF3 Diagnosis Biopsy Table [NCIt concept]
- CRF3 Diagnosis Re-Biopsy Table [NCIt concept]
- CRF7 Pathology Review Table [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCI CTEP SDC Astrocytoma, High Grade Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Grade 4 Lesion [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Necrotic Change [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Astrocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_associated_gene
- NEURL1 Gene [NCIt concept]
- NEURL1 wt Allele [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mitotic Activity [NCIt concept]
- Nuclear Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 6 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Deletion [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
human_disease_maps_to_eo_disease
- Mouse Anaplastic Astrocytoma [NCIt concept]
pathogenesis_of_disease_involves_gene
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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