" /> NEURL1 wt Allele - CISMeF





Preferred Label : NEURL1 wt Allele;

NCIt synonyms : Neuralized (Drosophila)-Like Gene; h-neu; RNF67; Neuralized Homolog (Drosophila) Gene; NEURL; NEURL wt Allele; bA416N2.1; neu-1; Neuralized-Like (Drosophila) Gene; NEUR1; Neuralized E3 Ubiquitin Protein Ligase 1 wt Allele;

NCIt definition : Human NEURL1 wild-type allele is located in the vicinity of 10q24.33 and is approximately 98 kb in length. This allele, which encodes E3 ubiquitin-protein ligase NEURL1 protein, plays a role in the regulation of proteasome-mediated protein degradation. The gene exhibits loss of heterozygosity in astrocytomas.;

NCIt note : The NEURL gene has been proposed to be involved in the determination of cell fate in the developing central nervous system. It is a putative tumor suppressor gene in astrocytomas.;

GenBank Accession Number : NM_004210;

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01/05/2025


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