Esophageal Adenocarcinoma

Preferred Label : Esophageal Adenocarcinoma;

NCIt synonyms : Esophagus Adenocarcinoma; Adenocarcinoma of Esophagus;

NCIt related terms : Adenocarcinoma; Adenocarcinoma of the esophagus; Adenocarcinoma - esophagus;

NCIt definition : A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.;

Neoplastic status : Malignant;

Codes from synonyms : 10030139;

Details

Origin ID

C4025;

UMLS CUI

C0279628;

Automatic exact mappings (from CISMeF team)
- Adenocarcinoma [MedDRA Preferred Term]
- Adenocarcinoma [PASCAL descriptor]
- Adenocarcinoma of oesophagus [ICD-11 Subcategory]
- Adenocarcinoma, no subtype (morphologic abnormality) [SNOMED CT concept]
- Barrett esophagus [OMIM Phenotype]
- Malignant adenomatous neoplasm (disorder) [SNOMED CT concept]
- adenocarcinoma [MeSH Descriptor]
- adenocarcinoma [DO Concept]
- adenocarcinoma [MeSH concept]
- adenocarcinoma [Radlex concept]
- esophagus adenocarcinoma [DO Concept]
Currated CISMeF NLP mapping
- Adenocarcinoma of esophagus [MedDRA LLT]
- Adenocarcinoma of esophagus (disorder) [SNOMED CT concept]
- Adenocarcinoma of oesophagus [MedDRA LLT]
- Adenocarcinoma of the esophagus [ORDO Disease]
- Esophageal adenocarcinoma [MedDRA LLT]
- Esophagus adenocarcinoma [PASCAL descriptor]
- Oesophageal adenocarcinoma [MedDRA Preferred Term]
- Oesophageal adenocarcinoma NOS [MedDRA LLT]
- adenocarcinoma of esophagus [MeSH concept]
- adenocarcinoma of esophagus [MeSH Supplementary Concept]
- esophageal adenocarcinoma [Disease (Nov.)]
DO Cross reference
- esophagus adenocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Adenocarcinoma of esophagus [MedDRA LLT]
- Adenocarcinoma of esophagus (disorder) [SNOMED CT concept]
- Adenocarcinoma of oesophagus [MedDRA LLT]
- Adenocarcinoma of the esophagus [ORDO Disease]
- Esophageal adenocarcinoma [MedDRA LLT]
- Oesophageal adenocarcinoma [MedDRA Preferred Term]
- Oesophageal adenocarcinoma NOS [MedDRA LLT]
- adenocarcinoma of esophagus [MeSH Supplementary Concept]
- adenocarcinoma of esophagus [MeSH concept]
- esophageal adenocarcinoma [Disease (Nov.)]
- esophagus adenocarcinoma [DO Concept]
associated_with_malfunction_of_gene_product
- Cathepsin B [NCIt concept]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Esophageal Carcinoma Baseline Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_associated_gene
- CTSB Gene [NCIt concept]
- CTSB wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Esophageal Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
- Esophagus and Gastroesophageal Junction [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 20q [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Loss of Chromosome 4q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Gene Amplification [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- FHIT Gene Inactivation [NCIt concept]
- Inactivating APC Gene Mutation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
pathogenesis_of_disease_involves_gene
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]

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