Barrett esophagus

Preferred Label : Barrett esophagus;

Type : Phenotype, molecular basis known;

Alternative titles and symbols : Barrett metaplasia;

Included titles and symbols : Adenocarcinoma of esophagus;

Description : Barrett esophagus, or Barrett metaplasia, describes the phenotypic change of normal esophageal squamous epithelium to a columnar and intestinal-type epithelium. This metaplastic change is important because patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett metaplasia is gastroesophageal reflux (GER; 109350). The retrograde movement of acid and bile salts from the stomach into the esophagus in this disease causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes (summary by Wong et al., 2005).;

Prefixed ID : #614266;

Details

Origin ID

614266;

UMLS CUI

C0004763;

Automatic exact mappings (from CISMeF team)
- Adenocarcinoma of esophagus [MedDRA LLT]
- Adenocarcinoma of esophagus (disorder) [SNOMED CT concept]
- Adenocarcinoma of the esophagus [ORDO Disease]
- Barrett's esophagus [ICD-9 code]
- Esophageal Adenocarcinoma [NCIt concept]
- Esophagus adenocarcinoma [PASCAL descriptor]
- Oesophageal adenocarcinoma [MedDRA Preferred Term]
- adenocarcinoma of esophagus [MeSH Supplementary Concept]
- adenocarcinoma of esophagus [MeSH concept]
- esophagus adenocarcinoma [DO Concept]
Currated CISMeF NLP mapping
- Barrett Esophagus [NCIt concept]
- Barrett esophagus [PASCAL descriptor]
- Barrett esophagus [Disease (Nov.)]
- Barrett esophagus [HPO term]
- Barrett esophagus [ORDO Disease]
- Barrett oesophagus [Artificial nutrition thesaurus concept]
- Barrett's esophagitis [MedDRA LLT]
- Barrett's esophagus [DO Concept]
- Barrett's esophagus [ICD-10 Sub-category]
- Barrett's esophagus [MedDRA LLT]
- Barrett's esophagus (disorder) [SNOMED CT concept]
- Barrett's oesophagitis [MedDRA LLT]
- Barrett's oesophagus [MedDRA Preferred Term]
- Barrett's ulcer of esophagus (disorder) [SNOMED CT concept]
- Columnar metaplastic epithelium of the oesophagus [ICD-11 Category]
- Endobrachyoesophagus [MedDRA LLT]
- Endobrachyooesophagus [MedDRA LLT]
- barrett esophagus [MeSH Descriptor]
- barrett esophagus [MeSH concept]
- barrett's esophagus [SNOMED Notion]
- columnar epithelium lined lower esophagus [Radlex concept]
- esophagus disorders [MedlinePlus Topic]
DO Cross reference
- Barrett's esophagus [DO Concept]
Genes related to phenotype
- Activating signal cointegrator 1 complex, subunit 1 [OMIM gene]
- Collagen triple-helix repeat-containing protein 1 [OMIM gene]
- Macrophage scavenger receptor [OMIM gene]
HPO term(s)
- Barrett esophagus [HPO term]
- Esophageal carcinoma [HPO term]
- Esophageal ulceration [HPO term]
- Gastroesophageal reflux [HPO term]
- Somatic mutation [HPO term]
ORDO concept(s)
- Adenocarcinoma of the esophagus [ORDO Disease]
- Barrett esophagus [ORDO Disease]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Barrett Esophagus [NCIt concept]
- Barrett epithelium [ICD-11 Subcategory]
- Barrett esophagus [ORDO Disease]
- Barrett esophagus [HPO term]
- Barrett esophagus [PASCAL descriptor]
- Barrett's esophagitis [MedDRA LLT]
- Barrett's esophagus [MedDRA LLT]
- Barrett's esophagus [ICD-10 Sub-category]
- Barrett's esophagus [DO Concept]
- Barrett's esophagus [ICD-9 code]
- Barrett's esophagus (disorder) [SNOMED CT concept]
- Barrett's oesophagitis [MedDRA LLT]
- Barrett's oesophagus [MedDRA Preferred Term]
- Endobrachyoesophagus [MedDRA LLT]
- Endobrachyooesophagus [MedDRA LLT]
- barrett esophagus [MeSH Descriptor]
- barrett esophagus [MeSH concept]
- barrett's esophagus [SNOMED Notion]
- columnar epithelium lined lower esophagus [Radlex concept]
Validated automatic mappings to BTNT
- Barrett's esophagus with esophagitis (disorder) [SNOMED CT concept]
Validated automatic mappings to NTBT
- esophageal adenocarcinoma [Disease (Nov.)]

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