" /> Esophagus - CISMeF





Preferred Label : Esophagus;

NCIt synonyms : Gastrointestinal Tract, Esophagus;

NCIt related terms : Esophagus, NOS; Oesophagus; Esophageal structure (body structure); gullet;

NCIt definition : The portion of the digestive canal between the pharynx and stomach. It is about 25 cm long and consists of three parts: the cervical part, from the cricoid cartilage to the thoracic inlet; thoracic part, from thoracic inlet to the diaphragm; and abdominal part, below the diaphragm to the cardiac opening of the stomach.;

Alternative definition : NCI-GLOSS: The muscular tube through which food passes from the throat to the stomach.; CDISC: The portion of the digestive tract between the pharynx and stomach.; UBERON: Tube that connects the pharynx to the stomach. In mammals, the esophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinized epithelium lining the buccal cavity is continued through the pharynx down into the esophagus. The lowest part of the esophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the esophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the esophagus enters the stomach to prevent gastro-esophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the esophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993).;

Codes from synonyms : CDR0000046408; 32849002;

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12/05/2025


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