Pathologic Stage III Esophageal Adenocarcinoma AJCC v8

Preferred Label : Pathologic Stage III Esophageal Adenocarcinoma AJCC v8;

NCIt related terms : Stage III Esophageal Adenocarcinoma; III;

NCIt definition : Stage III includes: IIIA: (T1, N2, M0, Any G); (T2, N1, M0, Any G); IIIB: (T2, N2, M0, Any G); (T3, N1-2, M0, Any G); (T4a, N0-1, M0, Any G). T1: Tumor invades the lamina propria, muscularis mucosae, or submucosa. T2: Tumor invades the muscularis propria. T3: Tumor invades adventitia. T4a: Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum. N0: No regional lymph node metastasis. N1: Tumor with metastasis in one or two regional lymph nodes. N2: Tumor with metastasis in three to six regional lymph nodes. M0: No distant metastasis. (AJCC 8th ed.);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL520870;

Details

Origin ID

C133421;

UMLS CUI

C4521653;

Automatic exact mappings (from CISMeF team)
- Esophageal adenocarcinoma stage III [MedDRA LLT]
- Oesophageal adenocarcinoma stage III [MedDRA Preferred Term]
- Roman numeral III (qualifier value) [SNOMED CT concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Esophageal Carcinoma Baseline Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Pathologic TNM Finding [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Esophageal Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
- Esophagus and Gastroesophageal Junction [NCIt concept]
disease_is_stage
- AJCC v8 Stage [NCIt concept]
- Stage III [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 20q [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Loss of Chromosome 4q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Gene Amplification [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- FHIT Gene Inactivation [NCIt concept]
- Inactivating APC Gene Mutation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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