Preferred Label : RASGRP1 wt Allele;

NCIt synonyms : MGC129998; CALDAG-GEFII; hRasGRP1; MGC129999; CALDAG-GEFI; RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) wt Allele; Guanine Nucleotide Exchange Factor, Calcium- and DAG-Regulated, Rap1A Gene; V; RASGRP;

NCIt definition : Human RASGRP1 wild-type allele is located in the vicinity of 15q14 and is approximately 77 kb in length. This allele, which encodes RAS guanyl-releasing protein 1, is involved in the modulation of small GTPase activation through its guanine nucleotide exchange activity. Mutation of the gene is associated with systemic lupus erythematosus.;

NCIt note : Cytogenetic abnormalities or mutations in the RASGRP1 gene may be associated with acute myeloid leukemia. (Nature Genetics. 2011; 43: 470-475.);

GenBank Accession Number : AF106071;

Détails


Consulter ci-dessous une sélection des principales ressources :

Vous pouvez consulter :


https://cps.ca/fr/documents/position/les-soins-aux-enfants-et-aux-adolescents-ayant-la-paralysie-cerebrale-aux-niveaux-iii-a-v-du-gmfcs
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