Esophageal Squamous Cell Carcinoma

Preferred Label : Esophageal Squamous Cell Carcinoma;

NCIt synonyms : Esophagus Squamous Cell Carcinoma; Esophagus SCC; SCC of Esophagus; Esophageal SCC; Squamous Cell Carcinoma of Esophagus; ESCC; SCC of the Esophagus; Esophageal Epidermoid Carcinoma; Esophageal Squamous Cell Carcinoma, Not Otherwise Specified; Esophageal Squamous Cell Carcinoma, NOS;

NCIt related terms : Esophageal Squamous Cell Cancer; Squamous cell carcinoma of the esophagus; Squamous cell car. - esophagus;

NCIt definition : A squamous cell carcinoma arising from the esophagus. It is associated with a long history of tobacco and alcohol abuse and is exceedingly rare before the age of 30. The median age is around 65 in both males and females. It is located mostly in the middle and lower third of the esophagus. Grossly, polypoid, ulcerated, plaque-like and occult lesions have been described. The microscopic features are the same as in other squamous cell carcinomas. Any degree of differentiation may occur, and variation within a single tumor is common. The prognosis is poor.;

Neoplastic status : Malignant;

Codes from synonyms : 10030186;

Details

Origin ID

C4024;

UMLS CUI

C0279626;

Automatic exact mappings (from CISMeF team)
- Squamous cell carcinoma of oesophagus [ICD-11 Subcategory]
- esophagus squamous cell carcinoma [DO Concept]
Currated CISMeF NLP mapping
- Esophageal Squamous Cell Carcinoma [MeSH Descriptor]
- Esophageal epidermoid carcinoma NOS [MedDRA LLT]
- Esophageal squamous cell carcinoma [MedDRA LLT]
- Esophagus squamous cell carcinoma [PASCAL descriptor]
- Oesophageal epidermoid carcinoma NOS [MedDRA LLT]
- Oesophageal squamous cell carcinoma [MedDRA Preferred Term]
- Oesophageal squamous cell carcinoma NOS [MedDRA LLT]
- Squamous cell carcinoma of esophagus [MedDRA LLT]
- Squamous cell carcinoma of esophagus (disorder) [SNOMED CT concept]
- Squamous cell carcinoma of esophagus NOS [MedDRA LLT]
- Squamous cell carcinoma of oesophagus [MedDRA LLT]
- Squamous cell carcinoma of the esophagus [ORDO Disease]
- esophageal squamous cell carcinoma [Disease (Nov.)]
- esophageal squamous cell carcinoma [MeSH concept]
DO Cross reference
- esophagus squamous cell carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Esophageal Squamous Cell Carcinoma [MeSH Descriptor]
- Esophageal epidermoid carcinoma NOS [MedDRA LLT]
- Esophageal squamous cell carcinoma [MedDRA LLT]
- Esophageal squamous cell carcinoma stage unspecified [MedDRA LLT]
- Esophagus squamous cell carcinoma [PASCAL descriptor]
- Oesophageal epidermoid carcinoma NOS [MedDRA LLT]
- Oesophageal squamous cell carcinoma [MedDRA Preferred Term]
- Oesophageal squamous cell carcinoma NOS [MedDRA LLT]
- Oesophageal squamous cell carcinoma stage unspecified [MedDRA LLT]
- Squamous cell carcinoma of esophagus [MedDRA LLT]
- Squamous cell carcinoma of esophagus (disorder) [SNOMED CT concept]
- Squamous cell carcinoma of esophagus NOS [MedDRA LLT]
- Squamous cell carcinoma of oesophagus [MedDRA LLT]
- Squamous cell carcinoma of the esophagus [ORDO Disease]
- esophageal squamous cell carcinoma [MeSH concept]
- esophageal squamous cell carcinoma [Disease (Nov.)]
- esophagus squamous cell carcinoma [DO Concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCI CTEP SDC Gastroesophageal Cancer Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_associated_gene
- DLEC1 Gene [NCIt concept]
- DLEC1 wt Allele [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Esophageal Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Esophageal Epithelium [NCIt concept]
- Esophageal Squamous Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
- Esophagus and Gastroesophageal Junction [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- del(17q25) [NCIt concept]
disease_may_have_molecular_abnormality
- Aneuploidy [NCIt concept]
- CCND1 Gene Amplification [NCIt concept]
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Gene Amplification [NCIt concept]
- FGF4 Gene Amplification [NCIt concept]
- FGF6 Gene Amplification [NCIt concept]
- FHIT Gene Inactivation [NCIt concept]
- MYC Gene Amplification [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
pathogenesis_of_disease_involves_gene
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]

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