Barrett Adenocarcinoma

Preferred Label : Barrett Adenocarcinoma;

NCIt synonyms : Barrett's Adenocarcinoma; Adenocarcinoma Arising in Barrett's Mucosa; Barrett s Adenocarcinoma;

NCIt definition : An adenocarcinoma arising from Barrett metaplastic epithelium in the esophagus. There is evidence supporting the idea that the Barrett adenocarcinomas develop through a stepwise progression through intestinal metaplastic epithelium to epithelial dysplasia to malignancy. Adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. In terms of grading, they are well or moderately differentiated adenocarcinomas.;

Neoplastic status : Malignant;

Details

Origin ID

C7027;

UMLS CUI

C1332460;

Automatic exact mappings (from CISMeF team)
- Barrett adenocarcinoma [ICD-11 Sub-sub category]
Currated CISMeF NLP mapping
- Barrett adenocarcinoma [Disease (Nov.)]
- Barrett's adenocarcinoma [DO Concept]
- Primary adenocarcinoma of lower third of esophagus due to Barrett esophagus (disorder) [SNOMED CT concept]
DO Cross reference
- Barrett's adenocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Dysphagia [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
- Lower Third of the Esophagus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Barrett's adenocarcinoma [DO Concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Metaplasia of Malignant Cells Present [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_associated_disease
- Barrett Esophagus [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Intestinal Metaplasia [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Metaplasia [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Esophageal Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
- Esophagus and Gastroesophageal Junction [NCIt concept]
- Lower Third of the Esophagus [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 20q [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Loss of Chromosome 4q [NCIt concept]
- Loss of Chromosome 5q [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Gene Amplification [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- FHIT Gene Inactivation [NCIt concept]
- Inactivating APC Gene Mutation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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