Esophageal Carcinoma Cuniculatum

Preferred Label : Esophageal Carcinoma Cuniculatum;

NCIt definition : An extremely rare, well-differentiated squamous cell carcinoma that arises from the esophagus. It is characterized by the presence of hyperkeratosis, acanthosis, dyskeratosis, keratin-filled cysts, koilocyte-like cells, intraepithelial neutrophils, and focal cytologic atypia.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1662348;

Details

Origin ID

C179888;

UMLS CUI

C5555931;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Low Grade Neuroendocrine Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Koilocytotic Squamous Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Acanthosis [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Dyskeratosis [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Focal Cytologic Atypia [NCIt concept]
- Hyperkeratosis [NCIt concept]
- Intraepithelial Neutrophils Present [NCIt concept]
- Keratin-Filled Cyst [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Prominent Keratin Formation [NCIt concept]
- Well Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Esophageal Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Esophageal Epithelium [NCIt concept]
- Esophageal Squamous Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Digestive System [NCIt concept]
- Esophagus [NCIt concept]
- Esophagus and Gastroesophageal Junction [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- del(17q25) [NCIt concept]
disease_may_have_molecular_abnormality
- Aneuploidy [NCIt concept]
- CCND1 Gene Amplification [NCIt concept]
- CDKN2A Gene Inactivation [NCIt concept]
- EGFR Gene Amplification [NCIt concept]
- FGF4 Gene Amplification [NCIt concept]
- FGF6 Gene Amplification [NCIt concept]
- Inactivating FHIT Gene Mutation [NCIt concept]
- MYC Gene Amplification [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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