Giant Cell Glioblastoma

Preferred Label : Giant Cell Glioblastoma;

NCIt definition : A rare histological variant of glioblastoma with a predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin network, and a high frequency of TP53 mutations. (WHO);

Neoplastic status : Malignant;

ICD-O code : 9441/3;

Details

Origin ID

C4325;

UMLS CUI

C0334588;

DO Cross reference
- giant cell glioblastoma [DO Concept]
Disease may have findings
- Headache [NCIt concept]
- Seizure [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Excludes anatomical site(s)
- Lymphatic System [NCIt concept]
Has associated anatomic sites
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Giant cell glioblastoma [ICD-O code]
- Giant cell glioblastoma [ICD-9 code]
- Giant cell glioblastoma [ORDO Disease]
- Giant cell glioblastoma [ICD-11 Extension code]
- Giant cell glioblastoma (morphologic abnormality) [SNOMED CT concept]
- Monstrocellular sarcoma (morphologic abnormality) [SNOMED CT concept]
- giant cell glioblastoma [DO Concept]
- giant cell glioblastoma [MeSH concept]
- giant cell glioblastoma [SNOMED Notion]
Validated automatic mappings to NTBT
- glioblastoma [MeSH Descriptor]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_excludes_molecular_abnormality
- IDH Gene Family Mutation [NCIt concept]
disease_has_abnormal_cell
- Giant Astrocyte [NCIt concept]
- Giant Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
- Poorly Differentiated Neoplastic Astrocyte [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Mitotic Activity [NCIt concept]
- Necrotic Change [NCIt concept]
- Nuclear Atypia [NCIt concept]
- Primary Lesion [NCIt concept]
disease_has_grade
- Grade 4 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Cell [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
- Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
disease_mapped_to_gene
- EGFR Gene [NCIt concept]
- TP53 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- EGFR Gene Amplification [NCIt concept]
- EGFR Protein Overexpression [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]
pathogenesis_of_disease_involves_gene
- TP53 Gene [NCIt concept]
- TP53 wt Allele [NCIt concept]
- TP53*1 Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients