Grade 4 - CISMeF

Preferred Label : Grade 4;

NCIt synonyms : Grade IV;

NCIt related terms : G4; 4; G4 Anaplastic; Undifferentiated Histology; undifferentiated; G4 Undifferentiated;

NCIt definition : A morphologic qualifier indicating that a cancerous lesion is undifferentiated.;

Alternative definition : NCI-GLOSS: A term used to describe cells or tissues that do not have specialized (mature) structures or functions. Undifferentiated cancer cells often grow and spread quickly.;

Codes from synonyms : CDR0000044775;

Details

Origin ID

C28082;

UMLS CUI

C0547054;

Automatic exact mappings (from CISMeF team)
- Grade 4 [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Grade 4 (qualifier value) [SNOMED CT concept]
- Grade IV [ICD-11 Extension code]
- grade 4 [Blood Transfusion thesaurus concept]
Semantic type(s)
- Classification [UMLS semantic type]
UMLS correspondences (same concept)
- Grade 4 (qualifier value) [SNOMED CT concept]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Head and Neck Squamous Cell Carcinoma Baseline Form [NCIt concept]
- CPTAC Lung Squamous Cell Carcinoma and Lung Adenocarcinoma Baseline Form [NCIt concept]
- CPTAC Pancreatic Baseline Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- ICDC Terminology [NCIt concept]
- ICDC Value Terminology [NCIt concept]
is_grade_of_disease
- Adult Brain Glioblastoma [NCIt concept]
- Adult Brain Stem Gliosarcoma [NCIt concept]
- Adult Central Nervous System Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Adult Diffuse Hemispheric Glioma, H3 G34-Mutant [NCIt concept]
- Adult Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Adult Diffuse Midline Glioma [NCIt concept]
- Adult Diffuse Midline Glioma, H3 K27-Altered [NCIt concept]
- Adult Diffuse Pediatric-Type High Grade Glioma MYCN [NCIt concept]
- Adult Diffuse Pediatric-Type High Grade Glioma RTK1 [NCIt concept]
- Adult Diffuse Pediatric-Type High Grade Glioma RTK2 [NCIt concept]
- Adult Diffuse Pediatric-Type High Grade Glioma, H3-Wildtype and IDH-Wildtype [NCIt concept]
- Adult Embryonal Tumor with Multilayered Rosettes, C19MC-Altered [NCIt concept]
- Adult Giant Cell Glioblastoma [NCIt concept]
- Adult Glioblastoma [NCIt concept]
- Adult Gliosarcoma [NCIt concept]
- Adult Medulloblastoma [NCIt concept]
- Adult Pineoblastoma [NCIt concept]
- Adult Spinal Cord Glioblastoma [NCIt concept]
- Adult Supratentorial Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Advanced Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Advanced Glioblastoma [NCIt concept]
- Advanced Rhabdoid Tumor [NCIt concept]
- Anaplastic Medulloblastoma [NCIt concept]
- Astrocytoma, IDH-Mutant, Grade 4 [NCIt concept]
- Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Atypical Teratoid/Rhabdoid Tumor Molecular Subtypes [NCIt concept]
- Atypical Teratoid/Rhabdoid Tumor-MYC [NCIt concept]
- Atypical Teratoid/Rhabdoid Tumor-SHH [NCIt concept]
- Atypical Teratoid/Rhabdoid Tumor-TYR [NCIt concept]
- Brain Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Brain Glioblastoma [NCIt concept]
- Brain Stem Glioblastoma [NCIt concept]
- Central Nervous System Embryonal Tumor [NCIt concept]
- Central Nervous System Embryonal Tumor with Rhabdoid Features [NCIt concept]
- Central Nervous System Embryonal Tumor, Not Elsewhere Classified [NCIt concept]
- Central Nervous System Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Central Nervous System Embryonal Tumor, Not Otherwise Specified with Leptomeningeal Spread [NCIt concept]
- Central Nervous System Ewing Sarcoma [NCIt concept]
- Central Nervous System Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor [NCIt concept]
- Central Nervous System Medulloepithelioma [NCIt concept]
- Central Nervous System Tumor with BCOR Internal Tandem Duplication [NCIt concept]
- Cerebellar Glioblastoma [NCIt concept]
- Cerebellar Vermis Medulloblastoma [NCIt concept]
- Cerebellopontine Angle Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Cerebral Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Cerebral Glioblastoma [NCIt concept]
- Childhood Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Childhood Brain Glioblastoma [NCIt concept]
- Childhood Brain Stem Gliosarcoma [NCIt concept]
- Childhood Central Nervous System Embryonal Tumor [NCIt concept]
- Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 Stage [NCIt concept]
- Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 Stage, Tier 1 [NCIt concept]
- Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 Stage, Tier 2 [NCIt concept]
- Childhood Central Nervous System Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Childhood Cerebral Embryonal Tumor with Multilayered Rosettes, C19MC-Altered [NCIt concept]
- Childhood Diffuse Hemispheric Glioma, H3 G34-Mutant [NCIt concept]
- Childhood Diffuse High Grade Glioma MYCN [NCIt concept]
- Childhood Diffuse High Grade Glioma RTK1 [NCIt concept]
- Childhood Diffuse High Grade Glioma RTK2 [NCIt concept]
- Childhood Diffuse High Grade Glioma, H3-Wildtype and IDH-Wildtype [NCIt concept]
- Childhood Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Childhood Diffuse Midline Glioma [NCIt concept]
- Childhood Diffuse Midline Glioma, H3 K27-Altered [NCIt concept]
- Childhood Embryonal Tumor with Multilayered Rosettes, C19MC-Altered [NCIt concept]
- Childhood Giant Cell Glioblastoma [NCIt concept]
- Childhood Glioblastoma [NCIt concept]
- Childhood Gliosarcoma [NCIt concept]
- Childhood Infratentorial Embryonal Tumor with Multilayered Rosettes, C19MC-Altered [NCIt concept]
- Childhood Medulloblastoma [NCIt concept]
- Childhood Medulloblastoma by Toronto Guidelines v2 Stage [NCIt concept]
- Childhood Medulloblastoma by Toronto Guidelines v2 Stage, Tier 1 [NCIt concept]
- Childhood Medulloblastoma by Toronto Guidelines v2 Stage, Tier 2 [NCIt concept]
- Childhood Pineoblastoma [NCIt concept]
- Childhood Supratentorial Embryonal Tumor with Multilayered Rosettes, C19MC-Altered [NCIt concept]
- Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Childhood WHO Grade 4 Glioma [NCIt concept]
- Classic Medulloblastoma [NCIt concept]
- Classical Glioblastoma [NCIt concept]
- Cribriform Neuroepithelial Tumor [NCIt concept]
- Desmoplastic/Nodular Medulloblastoma [NCIt concept]
- Diencephalic Glioblastoma [NCIt concept]
- Diffuse Hemispheric Glioma, H3 G34-Mutant [NCIt concept]
- Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Diffuse Midline Glioma [NCIt concept]
- Diffuse Midline Glioma with EZHIP Overexpression [NCIt concept]
- Diffuse Midline Glioma, EGFR-Mutant [NCIt concept]
- Diffuse Midline Glioma, H3 K27-Altered [NCIt concept]
- Diffuse Midline Glioma, H3 K27M-Mutant [NCIt concept]
- Diffuse Non-Pontine Midline Glioma [NCIt concept]
- Diffuse Pediatric-Type High Grade Glioma MYCN [NCIt concept]
- Diffuse Pediatric-Type High Grade Glioma RTK1 [NCIt concept]
- Diffuse Pediatric-Type High Grade Glioma RTK2 [NCIt concept]
- Diffuse Pediatric-Type High Grade Glioma, H3-Wildtype and IDH-Wildtype [NCIt concept]
- ELP1-Associated Medulloblastoma [NCIt concept]
- Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Embryonal Tumor with Multilayered Rosettes of the Fourth Ventricle [NCIt concept]
- Embryonal Tumor with Multilayered Rosettes without C19MC Alteration [NCIt concept]
- Embryonal Tumor with Multilayered Rosettes, C19MC-Altered [NCIt concept]
- Embryonal Tumor with Multilayered Rosettes, DICER1-Mutated [NCIt concept]
- Epithelioid Glioblastoma [NCIt concept]
- Extrarenal Rhabdoid Tumor [NCIt concept]
- Extrarenal Rhabdoid Tumor of the Liver [NCIt concept]
- Extrarenal Rhabdoid Tumor of the Ovary [NCIt concept]
- Extrarenal Rhabdoid Tumor of the Prostate [NCIt concept]
- Familial Adenomatous Polyposis Associated Medulloblastoma [NCIt concept]
- Fourth Ventricle Medulloblastoma [NCIt concept]
- Giant Cell Glioblastoma [NCIt concept]
- Glioblastoma [NCIt concept]
- Glioblastoma by Gene Expression Profile [NCIt concept]
- Glioblastoma with Primitive Neuronal Component [NCIt concept]
- Glioblastoma, IDH-Wildtype [NCIt concept]
- Glioblastoma, Not Otherwise Specified [NCIt concept]
- Gliosarcoma [NCIt concept]
- Grade 4 Clear Cell Renal Cell Carcinoma [NCIt concept]
- Grade 4 Malignant Neoplasm [NCIt concept]
- Granular Cell Glioblastoma [NCIt concept]
- Infratentorial Glioblastoma [NCIt concept]
- Large Cell Medulloblastoma [NCIt concept]
- Large Cell/Anaplastic Medulloblastoma [NCIt concept]
- Lipidized Glioblastoma [NCIt concept]
- Localized Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Localized Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Locally Advanced Glioblastoma [NCIt concept]
- MGMT-Methylated Glioblastoma [NCIt concept]
- MGMT-Unmethylated Glioblastoma [NCIt concept]
- Medulloblastoma [NCIt concept]
- Medulloblastoma Molecular Subtypes [NCIt concept]
- Medulloblastoma with Extensive Nodularity [NCIt concept]
- Medulloblastoma with Leptomeningeal Spread [NCIt concept]
- Medulloblastoma, Non-WNT/Non-SHH [NCIt concept]
- Medulloblastoma, Non-WNT/Non-SHH, Group 3 [NCIt concept]
- Medulloblastoma, Non-WNT/Non-SHH, Group 4 [NCIt concept]
- Medulloblastoma, Not Otherwise Specified [NCIt concept]
- Medulloblastoma, SHH-1 [NCIt concept]
- Medulloblastoma, SHH-2 [NCIt concept]
- Medulloblastoma, SHH-3 [NCIt concept]
- Medulloblastoma, SHH-4 [NCIt concept]
- Medulloblastoma, SHH-Activated [NCIt concept]
- Medulloblastoma, SHH-Activated, TP53-Mutant [NCIt concept]
- Medulloblastoma, SHH-Activated, TP53-Wildtype [NCIt concept]
- Medulloblastoma, WNT-Activated [NCIt concept]
- Medullomyoblastoma [NCIt concept]
- Melanocytic Medulloblastoma [NCIt concept]
- Mesenchymal Glioblastoma [NCIt concept]
- Metastatic Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Metastatic Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Metastatic Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Metastatic Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Metastatic Glioblastoma [NCIt concept]
- Metastatic Medulloblastoma [NCIt concept]
- Metastatic Rhabdoid Tumor [NCIt concept]
- Multifocal Glioblastomas [NCIt concept]
- Neural Glioblastoma [NCIt concept]
- Nevoid Basal Cell Carcinoma Syndrome Associated Medulloblastoma [NCIt concept]
- Optic Nerve Glioblastoma [NCIt concept]
- Pineoblastoma [NCIt concept]
- Pineoblastoma Molecular Subtypes [NCIt concept]
- Pineoblastoma miRNA Processing Altered 1 [NCIt concept]
- Pineoblastoma miRNA Processing Altered 2 [NCIt concept]
- Pineoblastoma, MYC/FOXR2-Activated [NCIt concept]
- Pineoblastoma, RB1-Altered [NCIt concept]
- Progressive Childhood Medulloblastoma [NCIt concept]
- Progressive Glioblastoma [NCIt concept]
- Progressive Medulloblastoma [NCIt concept]
- Progressive Medulloblastoma, SHH-Activated [NCIt concept]
- Proneural Glioblastoma [NCIt concept]
- Recurrent Astrocytoma, IDH-Mutant, Grade 4 [NCIt concept]
- Recurrent Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Recurrent Brain Glioblastoma [NCIt concept]
- Recurrent Childhood Central Nervous System Embryonal Tumor [NCIt concept]
- Recurrent Childhood Diffuse Midline Glioma [NCIt concept]
- Recurrent Childhood Giant Cell Glioblastoma [NCIt concept]
- Recurrent Childhood Glioblastoma [NCIt concept]
- Recurrent Childhood Gliosarcoma [NCIt concept]
- Recurrent Childhood Medulloblastoma [NCIt concept]
- Recurrent Childhood Pineoblastoma [NCIt concept]
- Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant [NCIt concept]
- Recurrent Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Recurrent Diffuse Midline Glioma [NCIt concept]
- Recurrent Diffuse Midline Glioma, H3 K27-Altered [NCIt concept]
- Recurrent Diffuse Midline Glioma, H3 K27M-Mutant [NCIt concept]
- Recurrent Extrarenal Rhabdoid Tumor [NCIt concept]
- Recurrent Extrarenal Rhabdoid Tumor of the Ovary [NCIt concept]
- Recurrent Giant Cell Glioblastoma [NCIt concept]
- Recurrent Glioblastoma [NCIt concept]
- Recurrent Glioblastoma, IDH-Wildtype [NCIt concept]
- Recurrent Gliosarcoma [NCIt concept]
- Recurrent MGMT-Methylated Glioblastoma [NCIt concept]
- Recurrent Medulloblastoma [NCIt concept]
- Recurrent Medulloblastoma, SHH-Activated [NCIt concept]
- Recurrent Medulloblastoma, WNT-Activated [NCIt concept]
- Recurrent Rhabdoid Tumor [NCIt concept]
- Recurrent Rhabdoid Tumor of the Kidney [NCIt concept]
- Recurrent Small Cell Glioblastoma [NCIt concept]
- Recurrent Supratentorial Glioblastoma [NCIt concept]
- Recurrent WHO Grade 4 Glioma [NCIt concept]
- Refractory Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Refractory Childhood Central Nervous System Embryonal Tumor [NCIt concept]
- Refractory Childhood Glioblastoma [NCIt concept]
- Refractory Childhood Medulloblastoma [NCIt concept]
- Refractory Diffuse Intrinsic Pontine Glioma [NCIt concept]
- Refractory Diffuse Midline Glioma, H3 K27M-Mutant [NCIt concept]
- Refractory Extrarenal Rhabdoid Tumor [NCIt concept]
- Refractory Extrarenal Rhabdoid Tumor of the Ovary [NCIt concept]
- Refractory Giant Cell Glioblastoma [NCIt concept]
- Refractory Glioblastoma [NCIt concept]
- Refractory Gliosarcoma [NCIt concept]
- Refractory Medulloblastoma [NCIt concept]
- Refractory Medulloblastoma, SHH-Activated [NCIt concept]
- Refractory Medulloblastoma, WNT-Activated [NCIt concept]
- Refractory Rhabdoid Tumor [NCIt concept]
- Refractory Rhabdoid Tumor of the Kidney [NCIt concept]
- Refractory Small Cell Glioblastoma [NCIt concept]
- Refractory WHO Grade 4 Glioma [NCIt concept]
- Region 17p13 Allelic Loss Associated Medulloblastoma [NCIt concept]
- Resectable Glioblastoma [NCIt concept]
- Rhabdoid Tumor [NCIt concept]
- Rhabdoid Tumor of the Kidney [NCIt concept]
- Secondary Glioblastoma [NCIt concept]
- Small Cell Glioblastoma [NCIt concept]
- Spinal Cord Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Spinal Cord Glioblastoma [NCIt concept]
- Stage M0 Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Stage M0 Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Stage M0 Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Stage M0 Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Stage M0 Medulloblastoma [NCIt concept]
- Stage M0 Pineoblastoma [NCIt concept]
- Stage M1 Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Stage M1 Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Stage M1 Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Stage M1 Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Stage M1 Medulloblastoma [NCIt concept]
- Stage M1 Pineoblastoma [NCIt concept]
- Stage M2 Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Stage M2 Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Stage M2 Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Stage M2 Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Stage M2 Medulloblastoma [NCIt concept]
- Stage M2 Pineoblastoma [NCIt concept]
- Stage M3 Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Stage M3 Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Stage M3 Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Stage M3 Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Stage M3 Medulloblastoma [NCIt concept]
- Stage M3 Pineoblastoma [NCIt concept]
- Stage M4 Atypical Teratoid/Rhabdoid Tumor [NCIt concept]
- Stage M4 Childhood Central Nervous System Embryonal Tumor by Toronto Guidelines v2 [NCIt concept]
- Stage M4 Childhood Medulloblastoma by Toronto Guidelines v2 [NCIt concept]
- Stage M4 Embryonal Tumor with Multilayered Rosettes [NCIt concept]
- Stage M4 Medulloblastoma [NCIt concept]
- Stage M4 Pineoblastoma [NCIt concept]
- Supratentorial Embryonal Tumor, Not Otherwise Specified [NCIt concept]
- Supratentorial Glioblastoma [NCIt concept]
- Supratentorial Gliosarcoma [NCIt concept]
- Unresectable Diffuse Hemispheric Glioma, H3 G34-Mutant [NCIt concept]
- Unresectable Diffuse Midline Glioma [NCIt concept]
- Unresectable Diffuse Midline Glioma, H3 K27M-Mutant [NCIt concept]
- Unresectable Extrarenal Rhabdoid Tumor [NCIt concept]
- Unresectable Glioblastoma [NCIt concept]
- Unresectable Rhabdoid Tumor [NCIt concept]
- Unresectable Rhabdoid Tumor of the Kidney [NCIt concept]
- WHO Grade 4 Glioma [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients