Preferred Label : Diffuse Pediatric-Type High Grade Glioma, H3-Wildtype and IDH-Wildtype;
NCIt synonyms : Diffuse Pediatric-Type High-Grade Glioma, H3-Wildtype and IDH-Wildtype; Pediatric-Type Glioblastoma, H3-Wildtype;
NCIt definition : An aggressive, WHO grade 4 diffuse brain glioma usually affecting children, adolescents,
or young adults. It is characterized by the absence of histone H3, IDH1, and IDH2
mutations. It includes the following subtypes, based on DNA methylation profiles:
diffuse pediatric-type high grade glioma RTK1, diffuse pediatric-type high grade glioma
RTK2, and diffuse pediatric-type high grade glioma MYCN.;
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL1773755;
Origin ID : C185467;
UMLS CUI : C5669918;
Disease may have findings
- Excludes anatomical site(s)
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_excludes_molecular_abnormality
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_grade
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
