Medulloblastoma, Non-WNT/Non-SHH, Group 3

Preferred Label : Medulloblastoma, Non-WNT/Non-SHH, Group 3;

NCIt related terms : Medulloblastoma, group 3;

NCIt definition : Medulloblastoma not associated with activation of the WNT pathway or sonic hedgehog (SHH) pathway. MYC amplifications may be present. TP53 mutations are absent. Patients in this group are usually young children. The overall survival is the worst among all the molecular groups.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL512711;

Details

Origin ID

C129445;

UMLS CUI

C4330665;

Automatic exact mappings (from CISMeF team)
- medulloblastoma non-WNT/non-SHH group 3 [DO Concept]
DO Cross reference
- medulloblastoma non-WNT/non-SHH group 3 [DO Concept]
Disease may have findings
- Ataxic Gait [NCIt concept]
- Headache [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
- Vomiting [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebellum [NCIt concept]
- Infratentorial Brain [NCIt concept]
- Nervous System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Multilayered Rosette Formation [NCIt concept]
- Sonic Hedgehog/Patch Pathway Activated [NCIt concept]
- WNT Pathway Activated [NCIt concept]
disease_excludes_molecular_abnormality
- TP53 Gene Mutation [NCIt concept]
disease_excludes_normal_tissue_origin
- Germinal Layer [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Neuroectodermal Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
disease_has_grade
- Grade 4 [NCIt concept]
disease_has_normal_cell_origin
- Embryonic Cell [NCIt concept]
disease_has_normal_tissue_origin
- Embryonic Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebellum [NCIt concept]
disease_may_have_molecular_abnormality
- MYC Gene Amplification [NCIt concept]

Keyword's position in hierarchy(ies) :

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