Glioblastoma, IDH-Wildtype

Preferred Label : Glioblastoma, IDH-Wildtype;

NCIt synonyms : Primary Glioblastoma Multiforme; Primary Glioblastoma, IDH-Wildtype; Primary Glioblastoma; Glioblastoma, IDH Wildtype;

NCIt definition : A glioblastoma that arises de novo. It is more commonly seen in older patients. Mutations in IDH1 or IDH2 genes are not present.;

Neoplastic status : Malignant;

Details

Origin ID

C39750;

UMLS CUI

C1514422;

Automatic exact mappings (from CISMeF team)
- IDH-wildtype glioblastoma [DO Concept]
- glioblastoma [DO Concept]
DO Cross reference
- glioblastoma [DO Concept]
Disease may have findings
- Headache [NCIt concept]
- Seizure [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
See also inter- (CISMeF)
- brain glioblastoma [Disease (Nov.)]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_excludes_molecular_abnormality
- IDH Gene Family Mutation [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
- Poorly Differentiated Neoplastic Astrocyte [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Mitotic Activity [NCIt concept]
- Necrotic Change [NCIt concept]
- Nuclear Atypia [NCIt concept]
- Primary Lesion [NCIt concept]
disease_has_grade
- Grade 4 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
disease_mapped_to_gene
- EGFR Gene [NCIt concept]
disease_may_have_molecular_abnormality
- PTEN Gene Inactivation [NCIt concept]
pathogenesis_of_disease_involves_gene
- EGFR Gene [NCIt concept]
- EGFR wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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