Methylated-DNA-Protein-Cysteine Methyltransferase

Preferred Label : Methylated-DNA-Protein-Cysteine Methyltransferase;

NCIt synonyms : O6-Alkylguanine DNA Alkyltransferase; Methylguanine-DNA Methyltransferase; Alkylguanine DNA Alkyltransferase; EC 2.1.1.63; AGT; MGMT; DNA-6-O-Methylguanine[protein]-L-Cysteine S-Methyltransferase; Methylated-DNA Protein-Cysteine Methyltransferase; O-6-Methylguanine-DNA Alkyltransferase; O-6-Methylguanine-DNA-Alkyltransferase; O-6-Methylguanine-DNA Methyltransferase; Methylated-DNA--Protein-Cysteine Methyltransferase;

NCIt definition : Methylated-DNA-protein-cysteine methyltransferase (207 aa, 22 kDa) is encoded by the human MGMT gene. This protein is involved in both repair and dealkylation of DNA.;

Détails

Origin ID

C17315;

UMLS CUI

C1869171;

Currated CISMeF NLP mapping
- methylated-dna-protein-cysteine methyltransferase [SNOMED Notion]
False automatic mappings
- Angiotensinogen [OMIM Phenotype]
- Methylated-deoxyribonucleic acid-protein-cysteine methyltransferase (substance) [SNOMED CT concept]
OMIM relation
- Methylguanine-dna methyltransferase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MGMT protein, human [MeSH Supplementary Concept]
- MGMT protein, human [MeSH concept]
- Methylated-deoxyribonucleic acid-protein-cysteine methyltransferase (substance) [SNOMED CT concept]
- O(6)-Methylguanine-DNA methyltransferase [MeSH concept]
- O(6)-Methylguanine-DNA methyltransferase [MeSH Descriptor]
- methylated-dna-protein-cysteine methyltransferase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MGMT Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Prognostic Biomarker [NCIt concept]
gene_product_malfunction_associated_with_disease
- Breast Carcinoma [NCIt concept]
- Retinoblastoma [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Methylation [NCIt concept]
is_target
- O6-Benzylguanine [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients