O(6)-Methylguanine-DNA methyltransferase

Preferred Label : O(6)-Methylguanine-DNA methyltransferase;

MeSH definition : An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. EC 2.1.1.63.;

MeSH synonym : guanine-o(6)-alkyltransferase; methylated-dna-protein-cysteine s-methyltransferase; o(6)-agt; o(6)-alkylguanine-dna alkyltransferase; o(6)-meg-dna methyltransferase; o(6)-methylguanine methyltransferase; methylated dna protein cysteine s methyltransferase; s-methyltransferase, methylated-dna-protein-cysteine; o(6)-methylguanine dna transmethylase;

MeSH hyponym : DNA repair methyltransferase I; DNA repair methyltransferase II;

MeSH CAS label : DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase;

MeSH Related Number : 77271-19-3 (CAS RN);

Registry Number MeSH : EC 2.1.1.63;

Is substance : O;

UNII : EC 2.1.1.63;

Details

Origin ID

D019853;

UMLS CUI

C0069197;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Methylated-DNA-Protein-Cysteine Methyltransferase [NCIt concept]
- O-6-methylguanine-DNA methyltransferase [ORDO Gene]
- methylated-DNA-[protein]-cysteine S-methyltransferase activity [GO term]
- methylated-dna-protein-cysteine methyltransferase [SNOMED Notion]
Indexing information
- 6-benzyloxy-7-(2-fluoroethyl)-7H-purine-2-yl-amine [MeSH Supplementary Concept]
- 6-benzyloxy-9-(2-fluoroethyl)-9H-purin-2-yl-amine [MeSH Supplementary Concept]
- O(4)-benzylfolic acid [MeSH Supplementary Concept]
- O(6)-(1-cyclopentenylmethyl)guanine [MeSH Supplementary Concept]
- O(6)-(5-iodobenzyl)guanine [MeSH Supplementary Concept]
- O(6)-(5-iodothenyl)guanine [MeSH Supplementary Concept]
Record concept(s)
- DNA repair methyltransferase I [MeSH concept]
- DNA repair methyltransferase II [MeSH concept]
- O(6)-Methylguanine-DNA methyltransferase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ada protein, E coli [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Methylated-DNA-Protein-Cysteine Methyltransferase [NCIt concept]
- Methylated-deoxyribonucleic acid-protein-cysteine methyltransferase (substance) [SNOMED CT concept]
- methylated-dna-protein-cysteine methyltransferase [SNOMED Notion]

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