" /> Epithelial Discoidin Domain-Containing Receptor 1 - CISMeF





Preferred Label : Epithelial Discoidin Domain-Containing Receptor 1;

NCIt synonyms : Discoidin Domain Receptor Family Member 1; Cell Adhesion Kinase; DDR1; CD167A Antigen; TRKE; Discoidin Receptor Tyrosine Kinase; Protein-Tyrosine Kinase RTK 6; Neurotrophic Tyrosine Kinase Receptor Type 4; NTRK4; Mammarian Carcinoma Kinase 10; Neuroepithelial Tyrosine Kinase; Discoidin Domain Receptor; Epithelial-Specific Receptor Kinase; Tyrosine-Protein Kinase CAK; Receptor Tyrosine Kinase NEP; Tyrosine Kinase Receptor E; Tyrosine Kinase DDR; Protein-Tyrosine Kinase RTK-6; CD167 Antigen-Like Family Member A; EC 2.7.10.1; HGK2; Epithelial Discoidin Domain Receptor 1; MCK-10; Protein-Tyrosine Kinase 3A; CD167a; Epithelial Discoidin Domain Receptor-1;

NCIt definition : Epithelial discoidin domain-containing receptor 1 (913 aa, 101 kDa) is encoded by the human DDR1 gene. This protein plays a role in tyrosine phosphorylation, extracellular matrix catabolism and signal transduction.;

NCIt note : Epithelial discoidin domain-containing receptor 1 has extracellular Discoidin I motifs; GLY/PRO-rich domains likely required for ligand or substrate interaction; a F5/8 type C domain; and a novel N-terminal region with homology to a factor VIII domain. The C-terminal catalytic domain has type II receptor tyrosine kinase motifs.;

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28/04/2024


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