Abiraterone - CISMeF

Preferred Label : Abiraterone;

NCIt synonyms : 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol;

NCIt definition : A steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.;

UNII : G819A456D0;

InChIKey : GZOSMCIZMLWJML-VJLLXTKPSA-N;

CAS number : 154229-19-3;

Molecule name : CB 7598;

Chemical formula : C24H31NO;

Codes from synonyms : 6;

Details

Origin ID

C77333;

UMLS CUI

C0754011;

CISMeF manual mappings
- Abiraterone (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Abiraterone [LOINC component]
- Abiraterone (substance) [SNOMED CT concept]
- Product containing abiraterone (medicinal product) [SNOMED CT concept]
- abiraterone [ATC Code]
- abiraterone [MeSH concept]
- abiraterone [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- abiraterone [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]
has_salt_form
- Abiraterone Acetate [NCIt concept]
- Abiraterone Decanoate [NCIt concept]
- Abiraterone Sulfate [NCIt concept]
has_target
- Steroid 17-Alpha-Hydroxylase/17,20 Lyase [NCIt concept]
is_free_acid_or_base_form_of
- Abiraterone Acetate [NCIt concept]
- Abiraterone Decanoate [NCIt concept]
- Abiraterone Sulfate [NCIt concept]

Keyword's position in hierarchy(ies) :

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