Caveolin-1 - CISMeF

Preferred Label : Caveolin-1;

NCIt synonyms : Cell Growth-Inhibiting Protein 32; Caveolae Protein, 22kD; CAV1; VIP21; Caveolin 1, Caveolae Protein, 22kD; CAV; Caveolin 1;

NCIt definition : Caveolin-1 (178 aa, 20 kDa) is encoded by the human CAV1 gene. This protein plays a role in caveolae formation and function.;

NCIt note : Caveolins interact with G proteins and link alpha integrin to FYN tyrosine kinase, SHC, GRB2 and the RAS-ERK pathway in promoting cell cycle progression.;

Details

Origin ID

C17971;

UMLS CUI

C1527865;

Currated CISMeF NLP mapping
- caveolin 1 [MeSH Descriptor]
- caveolin 1 [MeSH concept]
OMIM relation
- Caveolin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CAV1 protein, human [MeSH concept]
- CAV1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- CAV1 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Kidney [NCIt concept]
- Liver [NCIt concept]
- Lung [NCIt concept]
- Muscle [NCIt concept]
gene_product_has_associated_anatomy
- Caveola [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Phosphoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Canonical Wnt Signaling Pathway [NCIt concept]
- Corticosteroid Cardioprotection Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Insulin Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Ion Channels in Vascular Endothelium Pathway [NCIt concept]
- Nitric Oxide Pathway [NCIt concept]
- PDGFR-alpha Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Prostate Carcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Mediated Endocytosis [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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