Collagen Alpha-2(V) Chain

Preferred Label : Collagen Alpha-2(V) Chain;

NCIt synonyms : Alpha 2 Type V Collagen; Collagen Type V Alpha 2; Type V Preprocollagen Alpha 2 Chain; COL5A2; Collagen Type V Alpha 2 Chain;

NCIt definition : Collagen alpha-2(V) chain (1499 aa, 145 kDa) is encoded by the human COL5A2 gene. This protein is involved in collagen fibril formation in connective tissues.;

NCIt note : Collagen alpha-2(V) chain is a constituent of type V collagen fibrils. Type V fibrillar collagen has several forms, the most common form is a trimer comprised of two collage alpha-1(V) chains and one alpha-2(V) chain. A placental form is a heterotrimer containing one alpha-1(V) chain, one alpha-2(V) chain, and one alpha-3(V) chain. (OMIM and UniProt);

NCI Metathesaurus CUI : CL1643229;

Details

Origin ID

C177530;

UMLS CUI

C5444636;

Automatic exact mappings (from CISMeF team)
- Collagen, type V, alpha-2 [OMIM gene]
- collagen type V alpha 2 chain [ORDO Gene]
- collagen type V alpha 2 chain [HGNC gene]
OMIM relation
- Collagen, type V, alpha-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- COL5A2 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Integrin Angiogenesis Pathway [NCIt concept]
- Syndecan-1-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Eye Development [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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