N-Telopeptide - CISMeF

Preferred Label : N-Telopeptide;

NCIt synonyms : Collagen Cross-Linked N-Telopeptide; NTx; Type I Collagen Cross-Linked N-Telopeptide; N-Terminal Type I Collagen Cross-Linked;

NCIt definition : This polypeptide is comprised of the amino terminal portions of fibrillar collagen, which are not part of the triple helical structure. Bone resorption of type I collagen by osteoclasts results in the release of this peptide. Thus, this polypeptide is utilized as a biomarker for bone loss.;

NCIt note : Triple helical collagen is constructed from more than one gene product; thus, N-telopeptides arise from heterogeneous sources.;

Details

Origin ID

C68563;

UMLS CUI

C0285526;

Automatic exact mappings (from CISMeF team)
- C-telopeptide [MeSH concept]
- C-telopeptide [MedDRA Preferred Term]
- Collagen crosslinked C-telopeptide [LOINC component]
- N-telopeptide [MeSH concept]
- Nose [LOINC System]
- Serotype NT/X (qualifier value) [SNOMED CT concept]
- collagen type I trimeric cross-linked peptide [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Collagen cross linked N-telopeptide (substance) [SNOMED CT concept]
- Collagen crosslinked N-telopeptide [LOINC component]
- N-telopeptide [MedDRA Preferred Term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- N-telopeptide [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_physical_part_of
- Type I Collagen [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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