Procollagen Type I C-Terminal Peptide

Preferred Label : Procollagen Type I C-Terminal Peptide;

NCIt synonyms : P1CP; Collagen Type 1 C-Terminal Propeptide; Procollagen Type 1 C-Terminal Peptide; Collagen Type I C-Terminal Propeptide; PICP;

NCIt definition : This polypeptide is comprised of the carboxy-terminal portions of procollagen, which are proteolytically removed by bone morphogenetic protein 1 during the intracellular formation of type I collagen fibrils. Increased plasma or serum concentrations of these peptides are associated with both fibrillogenesis of type I collagen and bone formation.;

NCIt note : Fibrillar collagen is constructed from more than one gene product; thus, procollagen C-terminal peptides arise from heterogeneous sources.;

Details

Origin ID

C116020;

UMLS CUI

C0072052;

Automatic exact mappings (from CISMeF team)
- collagen type i c-terminal propeptide [EMDN type]
- procollagen type I carboxy terminal peptide [MeSH Supplementary Concept]
- propeptide collagen type i c-terminal [medical devices type]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- procollagen type I carboxy terminal peptide [MeSH Supplementary Concept]
- procollagen type I carboxy terminal peptide [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_is_physical_part_of
- Type I Collagen [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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