CTX - CISMeF

Preferred Label : CTX;

NCIt synonyms : Cross-Linked C-Terminal Telopeptide of Type I Collagen; C-Terminal Telopeptide Type 1 Collagen; C-Telopeptide; C-Terminal Telopeptide Type I Collagen; CTXI; CTX-I; Collagen Type 1 Cross-linked C-Telopeptide;

NCIt definition : This polypeptide is comprised of the carboxy-terminal portions of fibrillar collagen, which are joined through trivalent crosslinks and released during the degradation of mature type I collagen by cathepsin K. Serum concentrations of these peptides can be correlated with the rate of bone metabolism.;

NCIt note : Triple helical collagen is constructed from more than one gene product; thus, C-telopeptides arise from heterogeneous sources.;

Details

Origin ID

C120031;

UMLS CUI

C5574748;

Automatic exact mappings (from CISMeF team)
- C-telopeptide [MeSH concept]
- C-telopeptide [MedDRA Preferred Term]
- C-terminal type I collagen telopeptide [MeSH concept]
- Cerebrotendinous xanthomatosis [OMIM Phenotype]
- Cerebrotendinous xanthomatosis [ORDO Disease]
- Collagen crosslinked C-telopeptide [LOINC component]
- Cyclophosphamide [LOINC component]
- Cyclophosphamide (substance) [SNOMED CT concept]
- Product containing cyclophosphamide (medicinal product) [SNOMED CT concept]
- collagen type I trimeric cross-linked peptide [MeSH Supplementary Concept]
- cytochrome P450 family 27 subfamily A member 1 [ORDO Gene]
False automatic mappings
- Cerebrotendinous xanthomatosis [ICD-11 More detail]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- C-telopeptide [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_physical_part_of
- Type I Collagen [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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