Collagen Alpha-1(VII) Chain

Preferred Label : Collagen Alpha-1(VII) Chain;

NCIt synonyms : Epidermolysis Bullosa, Dystrophic, Dominant And Recessive; Collagen VII, Alpha-1 Polypeptide; LC Collagen; Long-Chain Collagen; COL7A1;

NCIt definition : Collagen alpha-1(VII) chain (2944 aa, 295 kDa) is encoded by the human COL7A1 gene. This protein is involved in interactions between squamous epithelia and the basement membrane.;

NCIt note : Type VII collagen fibrils are composed of homotrimers of collagen alpha-1(VII) chain.;

Details

Origin ID

C107115;

UMLS CUI

C3812182;

Automatic exact mappings (from CISMeF team)
- Collagen, type VII, alpha-1 [OMIM gene]
- collagen type VII alpha 1 chain [ORDO Gene]
- collagen type VII alpha 1 chain [HGNC gene]
- collagen type vii [MeSH Descriptor]
OMIM relation
- Collagen, type VII, alpha-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- COL7A1 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Basement Membrane [NCIt concept]
- Collagen Fibril [NCIt concept]
- Extracellular Matrix [NCIt concept]
- Stratified Squamous Epithelium [NCIt concept]
gene_product_is_physical_part_of
- Type VII Collagen [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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