A Disintegrin and Metalloproteinase with Thrombospondin Motifs 10

Preferred Label : A Disintegrin and Metalloproteinase with Thrombospondin Motifs 10;

NCIt synonyms : A Disintegrin and Metalloproteinase with Thrombospondin Motifs-10; ADAMTS10; A Disintegrin and Metalloprotease with Thrombospondin Motifs-10; EC 3.4.24.-; ADAM-TS10; ADAMTS-10; ADAM-TS 10; A Disintegrin and Metalloprotease with Thrombospondin Motifs 10;

NCIt definition : A disintegrin and metalloproteinase with thrombospondin motifs 10 (1103 aa, 121 kDa) is encoded by the human ADAMTS10 gene. This protein plays a role in the assembly of extracellular microfibrils.;

Details

Origin ID

C190636;

UMLS CUI

C1530672;

Automatic exact mappings (from CISMeF team)
- A disintegrin-like and metalloproteinase with thrombospondin type 1 motif, 10 [OMIM gene]
- ADAM metallopeptidase with thrombospondin type 1 motif 10 [ORDO Gene]
OMIM relation
- A disintegrin-like and metalloproteinase with thrombospondin type 1 motif, 10 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ADAMTS10 protein, human [MeSH Supplementary Concept]
- ADAMTS10 protein, human [MeSH concept]
gene_encodes_gene_product
- ADAMTS10 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
- Fibrillin Microfibrils [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
- Peptidase Family M12B [NCIt concept]
gene_product_has_structural_domain_or_motif
- Disintegrin Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients