Thrombospondin-1

Preferred Label : Thrombospondin-1;

NCIt synonyms : TSP1; THBS1; TSP; TSP-1; Thrombospondin 1;

NCIt definition : Thrombospondin-1 (1170 aa, 129 kDa) is encoded by the human THBS1 gene. This protein plays a role in both cell-cell and cell-matrix interactions.;

NCI Metathesaurus CUI : CL599078;

Details

Origin ID

C17547;

UMLS CUI

C4307536;

Currated CISMeF NLP mapping
- thrombospondin 1 [MeSH Descriptor]
- thrombospondin 1 [MeSH concept]
OMIM relation
- Thrombospondin I [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
UMLS correspondences (same concept)
- thrombospondin 1 [MeSH concept]
- thrombospondin 1 [MeSH Descriptor]
- thrombospondin-1, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- THBS1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Endothelial Cell [NCIt concept]
- Platelet [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_biochemical_function
- Angiogenesis Inhibitory Protein [NCIt concept]
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- TSP-1 Induced Apoptosis Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Adrenal Cortical Neoplasm [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Metastasis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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