thrombospondin 1

Preferred Label : thrombospondin 1;

MeSH definition : An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.;

MeSH synonym : tsp-1;

CISMeF synonym : 1, thrombospondin;

MeSH annotation : a membrane glycoprotein;

Wikipedia link : https://en.wikipedia.org/wiki/Thrombospondin 1;

Is substance : O;

Details

Origin ID

D019700;

UMLS CUI

C0147139;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Thrombospondin-1 [NCIt concept]
Record concept(s)
- thrombospondin 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- Thbs1 protein, mouse [MeSH Supplementary Concept]
- acetyl-sarcosyl-glycyl-valyl-isoleucyl-threonyl-norvalyl-isoleucyl-arginyl-proline ethylamide [MeSH Supplementary Concept]
- cysteinyl-seryl-valyl-threonyl-cysteinyl-glycine [MeSH Supplementary Concept]
- thrombospondin 1, rat [MeSH Supplementary Concept]
- thrombospondin-1, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Thrombospondin-1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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