Laminin Subunit Gamma-2

Preferred Label : Laminin Subunit Gamma-2;

NCIt synonyms : Nicein Subunit Gamma; CSF 140 kDa Subunit; Laminin-5 Subunit Gamma; Epiligrin Subunit Gamma; Laminin-5 Gamma-2 Chain; Cell-Scattering Factor 140 kDa Subunit; BM600-100kDa; Large Adhesive Scatter Factor 140 kDa Subunit; Ladsin 140 kDa Subunit; Laminin B2t Chain; Kalinin/Nicein/Epiligrin 100 kDa Subunit; Kalinin Subunit Gamma;

NCIt definition : Laminin subunit gamma-2 (1193 aa, 131 kDa) is encoded by the human LAMC2 gene. This protein plays a role in both the organization of the extracellular matrix and the development of the epidermis.;

NCIt note : Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Laminin subunit gamma-2 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein). (UniProt);

Details

Origin ID

C116277;

UMLS CUI

C0910226;

Automatic exact mappings (from CISMeF team)
- laminin subunit gamma 2 [ORDO Gene]
OMIM relation
- Laminin, gamma-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LAMC2 protein, human [MeSH Supplementary Concept]
- LAMC2 protein, human [MeSH concept]
gene_encodes_gene_product
- Extracellular Matrix Protein Gene [NCIt concept]
- LAMC2 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Basal Lamina [NCIt concept]
- Extracellular Matrix [NCIt concept]
gene_product_has_biochemical_function
- Laminin [NCIt concept]
gene_product_is_element_in_pathway
- Alpha6/Beta1 and Alpha6/Beta4 Integrin Signaling Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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