Collagen Alpha-1(I) Chain

Preferred Label : Collagen Alpha-1(I) Chain;

NCIt synonyms : Collagen of Skin, Tendon, and Bone, Alpha-1 Chain; Collagen Alpha-1(I) Chain Preproprotein; Collagen I, Alpha-1 Polypeptide; Alpha 1 Type I Collagen; Collagen Alpha 1(I) Chain; Collagen, Type I, Alpha 1; Collagen of Skin, Tendon and Bone, Alpha-1 Chain; COL1A1; Collagen I Alpha-1; Alpha1(I) Procollagen; Type I Proalpha 1; Pro-Alpha-1 Collagen Type 1; Collagen I (Alpha 1); Alpha-1 Type I Collagen; Collagen Alpha 1 Chain Type I; Type I Procollagen Alpha 1 Chain;

NCIt definition : Collagen alpha-1(I) chain (1464 aa, 139 kDa) is encoded by the human COL1A1 gene. This protein is involved in the formation of fibrillar collagen.;

NCIt note : Type I collagen is a heterotrimer composed of one alpha 2(I) and two alpha 1(I) chains.;

Details

Origin ID

C30013;

UMLS CUI

C0972255;

Automatic exact mappings (from CISMeF team)
- Collagen, type I, alpha-1 [OMIM gene]
- Osteogenesis imperfecta type IV (disorder) [SNOMED CT concept]
- collagen type I [MeSH Descriptor]
- collagen type I alpha 1 chain [HGNC gene]
Currated CISMeF NLP mapping
- Collagen Type I, alpha 1 Chain [MeSH Descriptor]
- Collagen Type I, alpha 1 Chain [MeSH concept]
- collagen type I alpha 1 chain [ORDO Gene]
- collagen type I, alpha 1 chain [MeSH concept]
False automatic mappings
- Collagen, type I, alpha-1 [OMIM Phenotype]
- Osteogenesis imperfecta, type iv [OMIM Phenotype]
- osteogenesis imperfecta type IV [Disease (Nov.)]
OMIM relation
- Collagen, type I, alpha-1 [OMIM Phenotype]
See also inter- (CISMeF)
- Osteogenesis imperfecta type IV (disorder) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- COL1A1 protein, human [MeSH Supplementary Concept]
- collagen type I, alpha 1 chain [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- COL1A1 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
gene_product_is_physical_part_of
- Type I Collagen [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]
is_target
- Halofuginone Hydrobromide [NCIt concept]

Keyword's position in hierarchy(ies) :

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