Elafin - CISMeF

Preferred Label : Elafin;

NCIt synonyms : Skin-Derived Antileukoproteinase; WAP Four-Disulfide Core Domain Protein 14; Protease Inhibitor WAP3; Peptidase Inhibitor 3; ESI; SKALP; Elastase-Specific Inhibitor; PI3; PI-3; Trappin-2;

NCIt definition : Elafin (117 aa, 12 kDa) is encoded by the human PI3 gene. This protein plays a role in the inhibition of neutrophil and pancreatic elastase proteinase activity.;

Details

Origin ID

C105391;

UMLS CUI

C0142580;

Currated CISMeF NLP mapping
- Elafin (substance) [SNOMED CT concept]
- elafin [MeSH Descriptor]
- elafin [MeSH concept]
OMIM relation
- Proteinase inhibitor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PI3 protein, human [MeSH concept]
- PI3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Inhibitor Gene [NCIt concept]
- PI3 Gene [NCIt concept]
- Proteinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- WAP Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Inhibition [NCIt concept]
- Protein Degradation Inhibition [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients