elafin - CISMeF

Preferred Label : elafin;

MeSH definition : A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.;

MeSH synonym : protease inhibitor wap3; inhibitor wap3, protease; peptidase inhibitor 3, skin-derived; peptidase inhibitor 3, skin derived; skin derived antileukoproteinase; protease inhibitor 3, skin-derived; protease inhibitor 3, skin derived; skin-derived antileukoproteinase; antileukoproteinase, skin-derived;

Wikipedia link : https://en.wikipedia.org/wiki/Elafin;

Is substance : O;

Details

Origin ID

D053492;

UMLS CUI

C1579194;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Elafin [NCIt concept]
- Elafin (substance) [SNOMED CT concept]
Pharmacological action(s)
- protease inhibitors [MeSH Descriptor]
Record concept(s)
- elafin [MeSH concept]
Related MeSH Supplementary Concept(s)
- PI3 protein, human [MeSH Supplementary Concept]
- trappin-2 A62L [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Elafin (substance) [SNOMED CT concept]
- Product containing elafin (medicinal product) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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