protease inhibitors

Preferred Label : protease inhibitors;

MeSH definition : Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).;

MeSH synonym : endopeptidase inhibitors; protease inhibitor; peptide hydrolase inhibitors; hydrolase inhibitors, peptide; peptide peptidohydrolase inhibitors; inhibitors, peptide peptidohydrolase; peptidohydrolase inhibitors, peptide; antagonists, protease; antiproteases; inhibitors, peptidase; inhibitor, protease; inhibitors, endopeptidase; inhibitors, protease; peptidase inhibitors; protease antagonists; inhibitors, peptide hydrolase; Antiprotease; Endopeptidase Inhibitor; Inhibitor, Endopeptidase; Peptidase Inhibitor; Inhibitor, Peptidase; Peptide Hydrolase Inhibitor; Hydrolase Inhibitor, Peptide; Inhibitor, Peptide Hydrolase; Protease Antagonist; Antagonist, Protease; Peptide Peptidohydrolase Inhibitor; Inhibitor, Peptide Peptidohydrolase; Peptidohydrolase Inhibitor, Peptide;

MeSH annotation : PROTEASE INHIBITORY PROTEINS, SECRETORY is also available; DF: PROTEASE INHIB; PROTEASE INHIBITORY PROTEINS, SECRETORY is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Protease inhibitors;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D011480;

UMLS CUI

C0033607;

ATC code(s)
- indinavir [ATC Code]
- nelfinavir [ATC Code]
- protease inhibitors [ATC Code]
- proteinase inhibitors [ATC Code]
- ritonavir [ATC Code]
- saquinavir [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- IKBKG wt Allele [NCIt concept]
- Ichthyosis-prematurity syndrome [ORDO Disease]
- Immunoprecipitation [NCIt concept]
- Incontinentia pigmenti [OMIM Phenotype]
- Indeno[1,2,3-cd]pyrene [NCIt concept]
- Intraperitoneal [NCIt concept]
- Peptide hydrolase inhibitor (disposition) [SNOMED CT concept]
- Product containing peptide hydrolase inhibitor (product) [SNOMED CT concept]
- Product containing proteinase inhibitor (product) [SNOMED CT concept]
- Protease inhibitor (disposition) [SNOMED CT concept]
- Protease inhibitors [ICD-11 Extension code]
- Proteinase inhibitor (disposition) [SNOMED CT concept]
- Pulsatility Index [NCIt concept]
- SDHB wt Allele [NCIt concept]
- Substance with proteinase inhibitor mechanism of action (substance) [SNOMED CT concept]
- Ulcerative proctitis [ICD-11 Subcategory]
- protease inhibitor [COVID-19 Thesaurus concept]
- proteinase inhibitors [ATC Code]
CISMeF manual mappings
- Substance with peptide hydrolase inhibitor mechanism of action (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Protease Inhibitor [NCIt concept]
- protease inhibitors [ATC Code]
False automatic mappings
- Cisplatin/Irinotecan Regimen [NCIt concept]
- Intraperitoneal Route of Administration [NCIt concept]
Indexing information
- 1-aminocyclopropaneboronic acid [MeSH Supplementary Concept]
- 3,5-bis((4-nitrophenyl)methylidene)-1-prop-2-enoylpiperidin-4-one [MeSH Supplementary Concept]
- AG1801 [MeSH Supplementary Concept]
- AGL2019 [MeSH Supplementary Concept]
- BB 1268 [MeSH Supplementary Concept]
- CGS 24426A [MeSH Supplementary Concept]
- CGS 27023A [MeSH Supplementary Concept]
- CSTA protein, human [MeSH Supplementary Concept]
- Cst6 protein, rat [MeSH Supplementary Concept]
- F2 protease inhibitor [MeSH Supplementary Concept]
- NSC48300 [MeSH Supplementary Concept]
- PGE 1132881 [MeSH Supplementary Concept]
- PGE 4410186 [MeSH Supplementary Concept]
- PGE 9818266 [MeSH Supplementary Concept]
- SL 327 [MeSH Supplementary Concept]
- UK 77568 [MeSH Supplementary Concept]
- antiprotease C-II [MeSH Supplementary Concept]
- bdellin [MeSH Supplementary Concept]
- beta (1)-anticollagenase [MeSH Supplementary Concept]
- carboxypolymethylene [MeSH Supplementary Concept]
- epigallocatechin gallate [MeSH Supplementary Concept]
- gamma-anticollagenase [MeSH Supplementary Concept]
- kexstatin I, streptomyces platensis [MeSH Supplementary Concept]
- micropeptin HH960 [MeSH Supplementary Concept]
- micropeptin HH978 [MeSH Supplementary Concept]
- micropeptin HH992 [MeSH Supplementary Concept]
- morelloflavone [MeSH Supplementary Concept]
- trielin [MeSH Supplementary Concept]
- whey acidic proteins [MeSH Supplementary Concept]
Manual BTNT mappings - CISMeF
- Protease inhibitor protein (substance) [SNOMED CT concept]
- Substance with protease inhibitor mechanism of action (substance) [SNOMED CT concept]
MeSH Descriptor(s) used for indexing
- endopeptidases [MeSH Descriptor]
- exopeptidases [MeSH Descriptor]
- peptide hydrolases [MeSH Descriptor]
Record concept(s)
- protease inhibitors [MeSH concept]
See also
- proteinase inhibitory proteins, secretory [MeSH Descriptor]
See also (suggested by CISMeF)
- endopeptidases [MeSH Descriptor]
- peptide hydrolases [MeSH Descriptor]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- 1,10-phenanthroline [MeSH Supplementary Concept]
- 1,2-epoxy-3-(p-nitrophenoxy)propane [MeSH Supplementary Concept]
- 1,6-bis(cyclohexyloximinocarbonyl)hexane [MeSH Supplementary Concept]
- 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside [MeSH Supplementary Concept]
- 2-mercaptomethyl-3-guanidinoethylthiopropionic acid [MeSH Supplementary Concept]
- 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate [MeSH Supplementary Concept]
- 3-amino-2-hydroxy-4-phenylbutanoic acid [MeSH Supplementary Concept]
- 4-aminomethylbenzoic acid [MeSH Supplementary Concept]
- 4-hydroxymercuribenzoate [MeSH Supplementary Concept]
- 4-toluenesulfonyl fluoride [MeSH Supplementary Concept]
- Atazanavir Sulfate [MeSH Descriptor]
- BB 1101 [MeSH Supplementary Concept]
- Cilastatin, Imipenem Drug Combination [MeSH Descriptor]
- Darunavir [MeSH Descriptor]
- GC376 [MeSH Supplementary Concept]
- N-acetyltryptophan [MeSH Supplementary Concept]
- N-carboxy-3-phenylpropyl-alanyl-aminoisobutyric acid-tyrosyl-aminobenzoate [MeSH Supplementary Concept]
- SCH 32615 [MeSH Supplementary Concept]
- Simeprevir [MeSH Descriptor]
- TIMP1 protein, human [MeSH Supplementary Concept]
- TIMP2 protein, human [MeSH Supplementary Concept]
- TIMP3 protein, human [MeSH Supplementary Concept]
- TMC-310911 [MeSH Supplementary Concept]
- Timp1 protein, mouse [MeSH Supplementary Concept]
- UK-383,367 [MeSH Supplementary Concept]
- alpha 1-inhibitor 3 [MeSH Supplementary Concept]
- alpha-1-microglobulin [MeSH Supplementary Concept]
- amastatin [MeSH Supplementary Concept]
- antipain [MeSH Descriptor]
- antistasin [MeSH Supplementary Concept]
- asunaprevir [MeSH Supplementary Concept]
- batimastat [MeSH Supplementary Concept]
- benzyloxycarbonyl-Asp-CH2OC(O)-2,6-dichlorobenzene [MeSH Supplementary Concept]
- candoxatril [MeSH Supplementary Concept]
- candoxatrilat [MeSH Supplementary Concept]
- carbobenzoxy-leucyl-leucyl-norvalinal [MeSH Supplementary Concept]
- cilastatin [MeSH Descriptor]
- cobicistat mixture with darunavir [MeSH Supplementary Concept]
- ditekiren [MeSH Supplementary Concept]
- ecabet [MeSH Supplementary Concept]
- elafin [MeSH Descriptor]
- enalkiren [MeSH Supplementary Concept]
- epicatechin gallate [MeSH Supplementary Concept]
- globomycin [MeSH Supplementary Concept]
- indinavir [MeSH Descriptor]
- isoflurophate [MeSH Descriptor]
- ixazomib [MeSH Supplementary Concept]
- leupeptins [MeSH Descriptor]
- lopinavir [MeSH Descriptor]
- murinoglobulin [MeSH Supplementary Concept]
- nelfinavir [MeSH Descriptor]
- ovomacroglobulin [MeSH Supplementary Concept]
- pepstatin [MeSH Supplementary Concept]
- pepstatins [MeSH Descriptor]
- phenylmethylsulfonyl fluoride [MeSH Descriptor]
- phosphoramidon [MeSH Supplementary Concept]
- pigment epithelium-derived factor [MeSH Supplementary Concept]
- proteinase inhibitor I (plants) [MeSH Supplementary Concept]
- proteinase inhibitory proteins, secretory [MeSH Descriptor]
- racecadotril [MeSH Supplementary Concept]
- remikiren [MeSH Supplementary Concept]
- renin inhibitory peptide [MeSH Supplementary Concept]
- ritonavir [MeSH Descriptor]
- rupintrivir [MeSH Supplementary Concept]
- saquinavir [MeSH Descriptor]
- sch 34826 [MeSH Supplementary Concept]
- sch 39370 [MeSH Supplementary Concept]
- sepimostate mesilate [MeSH Supplementary Concept]
- thiorphan [MeSH Descriptor]
- ubenimex [MeSH Supplementary Concept]
- valyl-(aspartyl)4-lysyl-chloromethane [MeSH Supplementary Concept]
UMLS correspondences (same concept)
- Product containing peptide hydrolase inhibitor (product) [SNOMED CT concept]
- Protease Inhibitor [NCIt concept]
- Substance with peptide hydrolase inhibitor mechanism of action (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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