Preferred Label : Darunavir;
MeSH definition : An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.
Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered
in combination with other ANTI-HIV AGENTS.;
MeSH hyponym : prezista; darunavir ethanolate; UIC-94017; TMC 114; UIC 94017; UIC94017; Ethanolate, Darunavir; 114, TMC; TMC114; TMC-114;
MeSH CAS label : (3-((4-aminobenzenesulfonyl)isobutylamino)-1-benzyl-2-hydroxypropyl)carbamic acid
hexahydrofuro(2,3-b)furan-3-yl ester;
MeSH Related Number : 206361-99-1 (darunavir); 33O78XF0BW;
Wikipedia link : https://en.wikipedia.org/wiki/Darunavir;
Is substance : O;
UNII : YO603Y8113;
Origin ID : D000069454;
UMLS CUI : C1435444;
ATC code(s)
- Allowable qualifiers
- CISMeF manual mappings
- Pharmacological action(s)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- symtuza [MeSH Supplementary Concept]
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.
Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered
in combination with other ANTI-HIV AGENTS.
https://www.ema.europa.eu/medicines/human/EPAR/Darunavir-Krka
2018
false
United Kingdom
English
French
syndication feed
Darunavir
Darunavir
drugs, generic
europe
Darunavir 400mg tablet (product)
Product containing darunavir in oral dose form (medicinal product form)
Darunavir 600mg tablet (product)
hiv protease inhibitors
hiv infections
hiv protease inhibitors
drug evaluation
treatment outcome
drug approval
administration, oral
acquired immunodeficiency syndrome
HIV-1
drug therapy, combination
drug interactions
pregnancy
breast feeding
darunavir
drug evaluation
package leaflet
summary of product characteristics
---
https://www.ema.europa.eu/medicines/human/EPAR/darunavir-krka-dd
2018
false
United Kingdom
English
French
syndication feed
Darunavir
Darunavir
drugs, generic
europe
Darunavir 400mg tablet (product)
Product containing darunavir in oral dose form (medicinal product form)
hiv protease inhibitors
hiv infections
hiv protease inhibitors
drug evaluation
treatment outcome
drug approval
administration, oral
acquired immunodeficiency syndrome
HIV-1
drug therapy, combination
drug interactions
pregnancy
breast feeding
darunavir
drug evaluation
package leaflet
summary of product characteristics
---
https://www.has-sante.fr/portail/jcms/c_2876133/fr/prezista
2018
false
false
false
France
darunavir ethanolate
darunavir
treatment outcome
insurance, health, reimbursement
evaluation of the transparency committee
prezista
Darunavir
---
https://www.has-sante.fr/portail/jcms/c_2886171/fr/symtuza-darunavir-/cobicistat-/emtricitabine-/tenofovir-alafenamide-association-d-antiviraux
2018
false
false
false
France
French
drug combinations
treatment outcome
anti-hiv agents
hiv infections
adult
adolescent
administration, oral
Cytochrome P-450 CYP3A Inhibitors
hiv protease inhibitors
reverse transcriptase inhibitors
antivirals for systemic use
evaluation of the transparency committee
insurance, health, reimbursement
guidelines for drug use
Tenofovir
Darunavir
Cobicistat
tenofovir alafenamide
Emtricitabine
tenofovir alafenamide
adenine
Darunavir Ethanolate/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fumarate
---
https://www.has-sante.fr/portail/jcms/c_2863577/fr/symtuza
2018
false
false
false
France
French
drug combinations
treatment outcome
anti-hiv agents
hiv infections
adult
adolescent
administration, oral
Cytochrome P-450 CYP3A Inhibitors
hiv protease inhibitors
reverse transcriptase inhibitors
antivirals for systemic use
evaluation of the transparency committee
insurance, health, reimbursement
Tenofovir
Darunavir
Cobicistat
tenofovir alafenamide
Emtricitabine
tenofovir alafenamide
adenine
Darunavir Ethanolate/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fumarate
---
https://www.ema.europa.eu/medicines/human/EPAR/Symtuza
2017
false
false
false
United Kingdom
French
English
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug combinations
Darunavir
Cobicistat
drug approval
europe
treatment outcome
Emtricitabine
tenofovir alafenamide
anti-hiv agents
anti-hiv agents
hiv infections
product surveillance, postmarketing
adult
adolescent
administration, oral
tablets
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 CYP3A Inhibitors
hiv protease inhibitors
hiv protease inhibitors
reverse transcriptase inhibitors
reverse transcriptase inhibitors
tenofovir alafenamide
antivirals for systemic use
pregnancy
breast feeding
drug interactions
drug evaluation, preclinical
Tenofovir
Darunavir
Cobicistat
tenofovir alafenamide
Emtricitabine
tenofovir alafenamide
adenine
Darunavir Ethanolate/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fumarate
---
https://www.ema.europa.eu/medicines/human/EPAR/Darunavir-Mylan
2017
false
United Kingdom
English
French
syndication feed
Darunavir
Darunavir
drugs, generic
Product containing darunavir (medicinal product)
hiv protease inhibitors
hiv infections
hiv protease inhibitors
drug evaluation
treatment outcome
drug approval
drug labeling
tablets
administration, oral
acquired immunodeficiency syndrome
HIV-1
drug therapy, combination
drug interactions
pregnancy
breast feeding
darunavir
drug evaluation
package leaflet
summary of product characteristics
---
http://www.has-sante.fr/portail/jcms/c_2607076/fr/rezolsta
http://www.has-sante.fr/portail/jcms/c_2607076/fr/rezolsta-darunavir/cobicistat-antiretroviral
2016
false
France
French
evaluation of the transparency committee
hiv infections
human immunodeficiency virus i infection
Genotype drug resistance test positive
drug therapy, combination
Cobicistat
Darunavir
darunavir and cobicistat
guidelines for drug use
drug interactions
withholding treatment
treatment outcome
adult
HIV-1
hiv infections
drug combinations
administration, oral
drug synergism
hiv protease inhibitors
cytochrome p-450 cyp3a
cobicistat mixture with darunavir
---
http://www.has-sante.fr/portail/jcms/c_2621282/fr/prezista
2016
false
France
French
Darunavir
Darunavir
human immunodeficiency virus i infection
ritonavir
evaluation of the transparency committee
administration, oral
darunavir ethanolate
drug therapy, combination
HIV-1
hiv infections
hiv protease inhibitors
hiv protease inhibitors
adult
child
adolescent
treatment outcome
clinical trials, phase ii as topic
insurance, health, reimbursement
sulfonamides
sulfonamides
darunavir ethanolate
---
http://www.has-sante.fr/portail/jcms/c_1747988/fr/prezista-darunavir-inhibiteur-de-protease
2014
false
France
French
evaluation of the transparency committee
guidelines for drug use
Darunavir
Darunavir
insurance, health, reimbursement
administration, oral
hiv infections
adolescent
HIV-1
darunavir ethanolate
darunavir
treatment outcome
darunavir ethanolate
hiv protease inhibitors
hiv protease inhibitors
drug therapy, combination
---
https://www.ema.europa.eu/medicines/human/EPAR/Rezolsta
2014
false
United Kingdom
French
English
hiv protease inhibitors
Darunavir
Darunavir
Cobicistat
Cobicistat
darunavir and cobicistat
drug approval
europe
treatment outcome
adult
HIV-1
hiv infections
drug combinations
administration, oral
drug synergism
hiv protease inhibitors
cytochrome p-450 cyp3a
continuity of patient care
drug monitoring
drug interactions
pregnancy
breast feeding
controlled clinical trials as topic
drug evaluation, preclinical
summary of product characteristics
package leaflet
drug evaluation
syndication feed
cobicistat mixture with darunavir
cobicistat mixture with darunavir
---
http://www.meddispar.fr/Medicaments/PREZISTA-800-B-30/(type)/letter/(value)/P/(cip)/3400926788704
2013
false
France
French
Darunavir
drug information
administration, oral
darunavir ethanolate
darunavir
drug prescriptions
legislation, drug
---
http://www.meddispar.fr/Medicaments/PREZISTA-100-B-1/(type)/letter/(value)/P/(cip)/3400926704957
2013
false
France
French
Darunavir
drug information
pharmaceutical solutions
administration, oral
darunavir ethanolate
darunavir
drug prescriptions
legislation, drug
---
http://www.has-sante.fr/portail/jcms/c_1525564/prezista
2013
false
France
French
Darunavir
Darunavir
evaluation of the transparency committee
administration, oral
darunavir ethanolate
drug therapy, combination
HIV-1
hiv infections
hiv protease inhibitors
hiv protease inhibitors
adult
child
adolescent
treatment outcome
clinical trials, phase ii as topic
insurance, health, reimbursement
darunavir ethanolate
---
https://www.ema.europa.eu/medicines/human/EPAR/Prezista
2012
false
United Kingdom
English
French
syndication feed
Darunavir
Darunavir
hiv protease inhibitors
hiv infections
hiv protease inhibitors
drug evaluation
treatment outcome
drug approval
drug labeling
tablets
administration, oral
acquired immunodeficiency syndrome
HIV-1
drug therapy, combination
drug interactions
pregnancy
breast feeding
darunavir
darunavir ethanolate
drug evaluation
package leaflet
summary of product characteristics
---
http://www.has-sante.fr/portail/jcms/c_1352584/prezista
http://www.has-sante.fr/portail/upload/docs/evamed/CT-12454_PREZISTA%20Gamme_RI_P1_CT%2012454.pdf
http://www.has-sante.fr/portail/jcms/c_900460/prezista
http://www.has-sante.fr/portail/jcms/c_1060966/prezista-ct-7149-7150-version-anglaise
2012
false
France
French
English
Darunavir
evaluation of the transparency committee
administration, oral
insurance, health, reimbursement
darunavir ethanolate
darunavir
HIV-1
hiv infections
adult
adolescent
child
hiv protease inhibitors
treatment outcome
---
http://www.has-sante.fr/portail/jcms/c_1198434/prezista-400-mg-darunavir-inhibiteur-de-protease-synthese-d-avis
2011
false
France
French
evaluation of the transparency committee
guidelines for drug use
Darunavir
Darunavir
insurance, health, reimbursement
administration, oral
hiv infections
adult
HIV-1
darunavir ethanolate
darunavir
treatment outcome
clinical trials, phase iii as topic
randomized controlled trials as topic
darunavir ethanolate
hiv protease inhibitors
hiv protease inhibitors
drug therapy, combination
---
http://www.has-sante.fr/portail/jcms/c_1172428/prezista
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-01/prezista_14-12-2011_avis_ct11428.pdf
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-11/prezista_ct_11428.pdf
2011
false
France
French
English
evaluation of the transparency committee
Darunavir
Darunavir
darunavir
administration, oral
insurance, health, reimbursement
hiv protease inhibitors
HIV-1
adult
hiv infections
treatment outcome
clinical trials, phase iii as topic
randomized controlled trials as topic
darunavir ethanolate
darunavir ethanolate
hiv protease inhibitors
---
http://www.meddispar.fr/medicaments/3959536
2010
false
France
French
Darunavir
tablets
administration, oral
legislation, drug
drug prescriptions
darunavir
darunavir ethanolate
drug information
---
http://www.meddispar.fr/medicaments/3959513
2010
false
France
French
Darunavir
darunavir
tablets
administration, oral
legislation, drug
drug prescriptions
darunavir ethanolate
drug information
---
http://www.has-sante.fr/portail/jcms/c_929080/prezista-darunavir-inhibiteur-de-protease
2010
false
France
French
Darunavir
hiv protease inhibitors
darunavir
child
drug therapy, combination
HIV-1
hiv infections
adolescent
acquired immunodeficiency syndrome
treatment outcome
darunavir ethanolate
evaluation of the transparency committee
---
http://www.meddispar.fr/index.php/medicaments/3931408
2009
false
France
French
Darunavir
darunavir
drug prescriptions
legislation, drug
tablets
administration, oral
darunavir ethanolate
drug information
---
http://www.has-sante.fr/portail/jcms/c_882764/synthese-d-avis-prezista-ct-6572-6833
http://www.has-sante.fr/portail/jcms/c_816312/prezista-ct-6572-6833
http://www.has-sante.fr/portail/jcms/c_882765/prezista-300-mg-et-600-mg-darunavir-inhibiteur-de-protease
2009
false
France
French
Darunavir
Darunavir
darunavir ethanolate
hiv infections
treatment outcome
hiv protease inhibitors
adult
HIV-1
administration, oral
darunavir
insurance, health, reimbursement
drug therapy, combination
hiv protease inhibitors
evaluation of the transparency committee
guidelines for drug use
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Prezista_HIV_October-14-2009_f.pdf
2009
false
Canada
French
Darunavir
darunavir ethanolate
darunavir
hiv infections
HIV-1
hiv protease inhibitors
adult
patient care management
drug evaluation
---
http://www.meddispar.fr/index.php/medicaments/3931383
2009
false
France
French
Darunavir
darunavir ethanolate
darunavir
drug prescriptions
legislation, drug
tablets
administration, oral
drug information
---
http://www.has-sante.fr/portail/jcms/c_882760/synthese-d-avis-prezista-ct-6571
http://www.has-sante.fr/portail/jcms/c_813779/prezista-ct-6571
http://www.has-sante.fr/portail/jcms/c_882761/prezista-400-mg-darunavir-inhibiteur-de-protease
2009
false
France
French
Darunavir
darunavir ethanolate
hiv infections
hiv protease inhibitors
drug therapy, combination
darunavir
insurance, health, reimbursement
adult
HIV-1
evaluation of the transparency committee
guidelines for drug use
---
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2008/14513a-fra.php
2008
false
Canada
French
English
Darunavir
darunavir ethanolate
Chemical and Drug Induced Liver Injury
hiv protease inhibitors
acute disease
liver diseases
drug monitoring
continuity of patient care
drug therapy, combination
adult
darunavir
pharmacovigilance note
patient education handout
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Prezista_Fr.pdf
2007
false
Canada
French
Darunavir
hiv infections
hiv protease inhibitors
darunavir ethanolate
darunavir
drug evaluation
---
