" /> Darunavir Ethanolate - CISMeF





Preferred Label : Darunavir Ethanolate;

NCIt definition : The ethanolate form of darunavir, a human immunodeficiency virus type 1 (HIV-1) protease nonpeptidic inhibitor, with activity against HIV. Upon oral administration, darunavir selectively targets and binds to the active site of HIV-1 protease, and inhibits the dimerization and catalytic activity of HIV-1 protease. This inhibits the proteolytic cleavage of viral Gag and Gag-Pol polyproteins in HIV-infected cells. This inhibition leads to the production of immature, non-infectious viral proteins that are unable to form mature virions, and prevents HIV replication.;

UNII : 33O78XF0BW;

InChIKey : QWSHKNICRJHQCY-VBTXLZOXSA-N;

CAS number : 635728-49-3;

Drug name : Prezista;

Molecule name : TMC114;

Chemical formula : C27H37N3O7S.C2H6O;

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20/08/2025


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