nucleic acid synthesis inhibitors

Preferred Label : nucleic acid synthesis inhibitors;

MeSH definition : Compounds that inhibit cell production of DNA or RNA.;

MeSH synonym : inhibitors, nucleic acid synthesis; Nucleic Acid Synthesis Inhibitor;

MeSH hyponym : DNA synthesis inhibitors; RNA synthesis inhibitors; DNA Polymerase Inhibitors; Synthesis Inhibitors, RNA; Inhibitors, RNA Synthesis; Inhibitors, DNA Polymerase; Polymerase Inhibitors, DNA; Synthesis Inhibitors, DNA; Inhibitors, DNA Synthesis; RNA Synthesis Inhibitor; Inhibitor, RNA Synthesis; Synthesis Inhibitor, RNA; DNA Polymerase Inhibitor; Inhibitor, DNA Polymerase; Polymerase Inhibitor, DNA; DNA Synthesis Inhibitor; Inhibitor, DNA Synthesis; Synthesis Inhibitor, DNA;

MeSH annotation : coordinate IM with DNA /biosyn (IM) or RNA /biosyn (IM) or specifc DNA or RNA / biosyn (IM);

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D019384;

UMLS CUI

C0376568;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DNA Polymerase Inhibitor [NCIt concept]
Currated CISMeF NLP mapping
- Nucleic Acid Synthesis Inhibitor [NCIt concept]
Indexing information
- artepillin C [MeSH Supplementary Concept]
- picornain 2A, picornavirus [MeSH Supplementary Concept]
MeSH Descriptor(s) used for indexing
- DNA-Directed DNA polymerase [MeSH Descriptor]
Record concept(s)
- DNA Polymerase Inhibitors [MeSH concept]
- DNA synthesis inhibitors [MeSH concept]
- RNA synthesis inhibitors [MeSH concept]
- nucleic acid synthesis inhibitors [MeSH concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- 1-(beta-D-arabinofuranosyl)-5-ethyluracil [MeSH Supplementary Concept]
- 1-O-(6'-sulfo-alpha-D-glucopyranosyl)-2,3-di-O-phytanyl-sn-glycerol [MeSH Supplementary Concept]
- 1-beta-arabinofuranosyl-5-butyluracil-5'-triphosphate [MeSH Supplementary Concept]
- 1-beta-arabinofuranosyl-5-ethyluracil 5'-triphosphate [MeSH Supplementary Concept]
- 1-beta-arabinofuranosyl-5-propyluracil-5'-triphosphate [MeSH Supplementary Concept]
- 1-deoxyrubralactone [MeSH Supplementary Concept]
- 2',3'-dideoxyguanosine [MeSH Supplementary Concept]
- 2,6-diaminopurine [MeSH Supplementary Concept]
- 2-hexaprenylhydroquinone [MeSH Supplementary Concept]
- 3,4-di-O-galloyl-5-O-digalloylquinic acid [MeSH Supplementary Concept]
- 4-n-butylanilino dATP [MeSH Supplementary Concept]
- 5-((1-(2-bromobenzoyl)-5-chloro-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione [MeSH Supplementary Concept]
- 5-(2-bromoethyl)-2'-deoxyuridine [MeSH Supplementary Concept]
- 5-(2-bromovinyl)uridine [MeSH Supplementary Concept]
- 5-(2-chloroethyl)-2'-deoxyuridine [MeSH Supplementary Concept]
- 9-beta-D-arabinofuranosylguanosine 5'-triphosphate [MeSH Supplementary Concept]
- DAAP1 [MeSH Supplementary Concept]
- Famciclovir [MeSH Descriptor]
- G(8-5m)T [MeSH Supplementary Concept]
- ITBA-16 [MeSH Supplementary Concept]
- Ibezapolstat [MeSH Supplementary Concept]
- Mercaptopurine [MeSH Descriptor]
- N(2)-(4-n-butylphenyl)-2'--deoxyguanosine 5'-imidotriphosphate [MeSH Supplementary Concept]
- Pemetrexed [MeSH Descriptor]
- Telbivudine [MeSH Descriptor]
- alpha-amanitin [MeSH Descriptor]
- amanitins [MeSH Descriptor]
- anisomycin [MeSH Descriptor]
- arabinofuranosyl-E-5-iodovinyluracil [MeSH Supplementary Concept]
- arabinofuranosylcytosine triphosphate [MeSH Descriptor]
- carbonyldiphosphonate [MeSH Supplementary Concept]
- chromomycin A3 [MeSH Descriptor]
- chromomycins [MeSH Descriptor]
- cytochalasin D [MeSH Descriptor]
- dactinomycin [MeSH Descriptor]
- dichlororibofuranosylbenzimidazole [MeSH Descriptor]
- digallic acid [MeSH Supplementary Concept]
- distamycins [MeSH Descriptor]
- echinomycin [MeSH Descriptor]
- edeine [MeSH Descriptor]
- fialuridine [MeSH Supplementary Concept]
- fluoroquinolones [MeSH Descriptor]
- fusaric acid [MeSH Descriptor]
- ganciclovir triphosphate [MeSH Supplementary Concept]
- hydroxyphenylazouracil [MeSH Descriptor]
- hydroxyurea [MeSH Descriptor]
- idoxuridine [MeSH Descriptor]
- lobucavir [MeSH Supplementary Concept]
- lucidenic acid O [MeSH Supplementary Concept]
- lucidenic lactone [MeSH Supplementary Concept]
- methotrexate [MeSH Descriptor]
- methylazoxymethanol acetate [MeSH Descriptor]
- mitomycin [MeSH Descriptor]
- nitracrine [MeSH Descriptor]
- nogalamycin [MeSH Descriptor]
- novobiocin [MeSH Descriptor]
- penciclovir triphosphate [MeSH Supplementary Concept]
- phleomycins [MeSH Descriptor]
- plicamycin [MeSH Descriptor]
- polycitone A [MeSH Supplementary Concept]
- rifampin [MeSH Descriptor]
- rimantadine [MeSH Descriptor]
- sch 725680 [MeSH Supplementary Concept]
- sculezonone A [MeSH Supplementary Concept]
- sculezonone B [MeSH Supplementary Concept]
- zinostatin [MeSH Descriptor]
UMLS correspondences (same concept)
- Nucleic Acid Synthesis Inhibitor [NCIt concept]

Keyword's position in hierarchy(ies) :

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