Preferred Label : hydroxyurea;

MeSH definition : An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.;

MeSH synonym : hydroxycarbamid;

Wikipedia automatic translation : Hydroxycarbamide;

MeSH hyponym : hydrea; oncocarbide;

MeSH CAS label : urea, hydroxy-;

MeSH Related Number : 127-07-1 (Hydroxyurea);

Registry Number MeSH : 127-07-1;

Wikipedia link : https://en.wikipedia.org/wiki/Hydroxycarbamide;

Codes EINECS : 204-821-7;

Is substance : O;

UNII : X6Q56QN5QC;

InChIKey : VSNHCAURESNICA-UHFFFAOYSA-N;

Details


Main resources

You can consult :

An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.

https://ansm.sante.fr/tableau-marr/hydroxycarbamide
2022
false
false
false
France
French
teratogens
hydroxyurea
hydroxyurea
continuity of patient care
guidelines for drug use
risk management
anemia, sickle cell
pain
adult
child
adolescent
fertility
pregnancy
contraception
blood cell count
hematologic diseases
patients guideline
package leaflet

---
https://www.cochrane.org/fr/CD002202/CF_hydroxyuree-egalement-appelee-hydroxycarbamide-chez-les-personnes-atteintes-de-drepanocytose
2022
false
true
false
France
United Kingdom
treatment outcome
review of literature
french abstract
hydroxyurea
anemia, sickle cell

---
https://www.has-sante.fr/jcms/p_3260466/fr/xromi
2021
false
false
false
France
treatment outcome
insurance, health, reimbursement
hydroxyurea
administration, oral
pharmaceutical solutions
child
adult
adolescent
anemia, sickle cell
guidelines for drug use
antisickling agents
vaso-occlusive complications of Sickle Cell Disease
Acute Chest Syndrome
evaluation of the transparency committee

---
https://www.ema.europa.eu/en/medicines/human/EPAR/xromi
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
hydroxyurea
hydroxyurea
adult
adolescent
child
anemia, sickle cell
Vaso-Occlusive Crisis
administration, oral
drug interactions
pregnancy
breast feeding
antisickling agents
antisickling agents
drug evaluation, preclinical
vaso-occlusive complications of Sickle Cell Disease

---
https://www.ansm.sante.fr/actualites/risque-de-confusion-entre-siklos-100-mg-et-siklos-1000-mg
2019
false
false
false
France
French
pharmacovigilance note
medication errors
hydroxyurea
child
adolescent
adult
administration, oral

---
https://devsante.org/articles/drepanocytose-traitement-par-l-hydroxyuree
2016
false
false
false
false
France
French
scientific and technical information
anemia, sickle cell
hydroxyurea

---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=66384911
2014
false
false
false
France
French
summary of product characteristics
package leaflet
hydroxyurea
dandruff
tablets
seborrhea sicca
hydroxyurea
pill, nos
compression, nos
dandruff

---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=66898948
2014
false
false
false
France
French
summary of product characteristics
package leaflet
tablets
hydroxyurea
compression, nos
hydroxyurea
dandruff
pill, nos
seborrhea sicca
dandruff

---
https://www.ema.europa.eu/medicines/human/EPAR/Siklos
2012
false
United Kingdom
English
French
syndication feed
Contraindications, Procedure
adult
hydroxyurea
treatment outcome
child
anemia, sickle cell
antisickling agents
antisickling agents
hydroxyurea
antisickling agents
hydroxyurea
antisickling agents
hydroxyurea
pregnancy
breast feeding
orphan drug production
hydroxycarbamide
drug evaluation
package leaflet
summary of product characteristics
Contraindications, Drug

---
http://www.meddispar.fr/Medicaments/SIKLOS-100-FL-60/(type)/letter/(value)/S/(cip)/3400941580574
2012
France
French
drug information
administration, oral
drug prescriptions
legislation, drug
continuity of patient care
pregnancy
hydroxyurea
antisickling agents

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66898948
2012
France
summary of product characteristics
package leaflet
hydroxyurea
tablets

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66384911
2012
France
summary of product characteristics
package leaflet
tablets
hydroxyurea

---
http://www.meddispar.fr/Medicaments/SIKLOS-1000-FL-30/(type)/letter/(value)/S/(cip)/3400938101942
2012
false
France
French
drug information
hydroxyurea
drug prescriptions
administration, oral
legislation, drug
continuity of patient care
antisickling agents
pregnancy

---
http://www.has-sante.fr/portail/jcms/c_1064176/siklos
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-06/siklos_-_ct-10560.pdf
2011
France
French
evaluation of the transparency committee
administration, oral
hydroxyurea
orphan drug production
child
anemia, sickle cell
pain
other hematological agents
treatment outcome
hydroxyurea
insurance, health, reimbursement

---
http://www.has-sante.fr/portail/jcms/c_1096057/siklos-100-mg-comprime-hydroxycarbamide
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-06/siklos_-_ct-10560.pdf
2011
France
French
evaluation of the transparency committee
guidelines for drug use
administration, oral
hydroxyurea
orphan drug production
insurance, health, reimbursement
child
anemia, sickle cell
pain
adult
adolescent
treatment outcome
hydroxyurea

---
http://www.cochrane.org/fr/CD003918
2011
false
true
false
France
United Kingdom
uterine cervical neoplasms
uterine cervical neoplasms
treatment outcome
review of literature
french abstract
hydroxyurea

---
https://hemato.chu-limoges.fr/hematolim/Portals/0/Info_patient/chimios/Fiche%20Hydr%C3%A9a.pdf
2010
false
true
false
France
hydroxyurea
popular works

---
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Hydroxyurea-for-Sickle-Cell-Disease.aspx
2009
false
Canada
English
French
child
anemia, sickle cell
hydroxyurea
hydroxyurea
antisickling agents
antisickling agents
administration, oral
drug information
patient education handout

---
http://www.has-sante.fr/portail/display.jsp?id=c_627641
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-5016_siklos_.pdf
2007
France
French
Cancer Pain
tablets
administration, oral
hydroxyurea
anemia, sickle cell
pain
antisickling agents
orphan drug production
hydroxycarbamide
insurance, health, reimbursement
child
adult
adolescent
treatment outcome
hydroxyurea
antisickling agents
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct032443.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_400865
2006
France
French
administration, oral
hydroxyurea
antineoplastic agents
insurance, health, reimbursement
hydroxycarbamide
leukemia, myeloid, chronic-phase
polycythemia vera
thrombocythemia, essential
primary myelofibrosis
evaluation of the transparency committee

---
https://www.amub-ulb.be/system/files/rmb/old/222
2006
Belgium
French
skin diseases
hydroxyurea
antineoplastic agents
journal article

---
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19/05/2024


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