Preferred Label : cytochalasin D;
MeSH definition : A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile
microfilament structures resulting in multinucleated cell formation, reversible inhibition
of cell movement, and the induction of cellular extrusion. Additional reported effects
include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose
transport, thyroid secretion, and growth hormone release.;
MeSH CAS label : (11)Cytochalasa-6(12),13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-,
(7S,13E,16S,18R,19E,21R)-;
Registry Number MeSH : 22144-77-0;
Is substance : O;
Origin ID : D015638;
UMLS CUI : C0010738;
Allowable qualifiers
Pharmacological action(s)
Record concept(s)
Semantic type(s)
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile
microfilament structures resulting in multinucleated cell formation, reversible inhibition
of cell movement, and the induction of cellular extrusion. Additional reported effects
include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose
transport, thyroid secretion, and growth hormone release.